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Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets
MOTIVATION: Visualization of genomic data is fundamental for gaining insights into genome function. Yet, co-visualization of a large number of datasets remains a challenge in all popular genome browsers and the development of new visualization methods is needed to improve the usability and user expe...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870560/ https://www.ncbi.nlm.nih.gov/pubmed/28334301 http://dx.doi.org/10.1093/bioinformatics/btx141 |
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author | Monfort, Matthias Furlong, Eileen E M Girardot, Charles |
author_facet | Monfort, Matthias Furlong, Eileen E M Girardot, Charles |
author_sort | Monfort, Matthias |
collection | PubMed |
description | MOTIVATION: Visualization of genomic data is fundamental for gaining insights into genome function. Yet, co-visualization of a large number of datasets remains a challenge in all popular genome browsers and the development of new visualization methods is needed to improve the usability and user experience of genome browsers. RESULTS: We present Dynamix, a JBrowse plugin that enables the parallel inspection of hundreds of genomic datasets. Dynamix takes advantage of a priori knowledge to automatically display data tracks with signal within a genomic region of interest. As the user navigates through the genome, Dynamix automatically updates data tracks and limits all manual operations otherwise needed to adjust the data visible on screen. Dynamix also introduces a new carousel view that optimizes screen utilization by enabling users to independently scroll through groups of tracks. AVAILABILITY AND IMPLEMENTATION: Dynamix is hosted at http://furlonglab.embl.de/Dynamix. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. |
format | Online Article Text |
id | pubmed-5870560 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-58705602018-04-05 Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets Monfort, Matthias Furlong, Eileen E M Girardot, Charles Bioinformatics Applications Notes MOTIVATION: Visualization of genomic data is fundamental for gaining insights into genome function. Yet, co-visualization of a large number of datasets remains a challenge in all popular genome browsers and the development of new visualization methods is needed to improve the usability and user experience of genome browsers. RESULTS: We present Dynamix, a JBrowse plugin that enables the parallel inspection of hundreds of genomic datasets. Dynamix takes advantage of a priori knowledge to automatically display data tracks with signal within a genomic region of interest. As the user navigates through the genome, Dynamix automatically updates data tracks and limits all manual operations otherwise needed to adjust the data visible on screen. Dynamix also introduces a new carousel view that optimizes screen utilization by enabling users to independently scroll through groups of tracks. AVAILABILITY AND IMPLEMENTATION: Dynamix is hosted at http://furlonglab.embl.de/Dynamix. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Oxford University Press 2017-07-15 2017-03-11 /pmc/articles/PMC5870560/ /pubmed/28334301 http://dx.doi.org/10.1093/bioinformatics/btx141 Text en © The Author 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Applications Notes Monfort, Matthias Furlong, Eileen E M Girardot, Charles Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets |
title | Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets |
title_full | Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets |
title_fullStr | Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets |
title_full_unstemmed | Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets |
title_short | Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets |
title_sort | dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets |
topic | Applications Notes |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870560/ https://www.ncbi.nlm.nih.gov/pubmed/28334301 http://dx.doi.org/10.1093/bioinformatics/btx141 |
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