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Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets

MOTIVATION: Visualization of genomic data is fundamental for gaining insights into genome function. Yet, co-visualization of a large number of datasets remains a challenge in all popular genome browsers and the development of new visualization methods is needed to improve the usability and user expe...

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Detalles Bibliográficos
Autores principales: Monfort, Matthias, Furlong, Eileen E M, Girardot, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870560/
https://www.ncbi.nlm.nih.gov/pubmed/28334301
http://dx.doi.org/10.1093/bioinformatics/btx141
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author Monfort, Matthias
Furlong, Eileen E M
Girardot, Charles
author_facet Monfort, Matthias
Furlong, Eileen E M
Girardot, Charles
author_sort Monfort, Matthias
collection PubMed
description MOTIVATION: Visualization of genomic data is fundamental for gaining insights into genome function. Yet, co-visualization of a large number of datasets remains a challenge in all popular genome browsers and the development of new visualization methods is needed to improve the usability and user experience of genome browsers. RESULTS: We present Dynamix, a JBrowse plugin that enables the parallel inspection of hundreds of genomic datasets. Dynamix takes advantage of a priori knowledge to automatically display data tracks with signal within a genomic region of interest. As the user navigates through the genome, Dynamix automatically updates data tracks and limits all manual operations otherwise needed to adjust the data visible on screen. Dynamix also introduces a new carousel view that optimizes screen utilization by enabling users to independently scroll through groups of tracks. AVAILABILITY AND IMPLEMENTATION: Dynamix is hosted at http://furlonglab.embl.de/Dynamix. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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spelling pubmed-58705602018-04-05 Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets Monfort, Matthias Furlong, Eileen E M Girardot, Charles Bioinformatics Applications Notes MOTIVATION: Visualization of genomic data is fundamental for gaining insights into genome function. Yet, co-visualization of a large number of datasets remains a challenge in all popular genome browsers and the development of new visualization methods is needed to improve the usability and user experience of genome browsers. RESULTS: We present Dynamix, a JBrowse plugin that enables the parallel inspection of hundreds of genomic datasets. Dynamix takes advantage of a priori knowledge to automatically display data tracks with signal within a genomic region of interest. As the user navigates through the genome, Dynamix automatically updates data tracks and limits all manual operations otherwise needed to adjust the data visible on screen. Dynamix also introduces a new carousel view that optimizes screen utilization by enabling users to independently scroll through groups of tracks. AVAILABILITY AND IMPLEMENTATION: Dynamix is hosted at http://furlonglab.embl.de/Dynamix. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Oxford University Press 2017-07-15 2017-03-11 /pmc/articles/PMC5870560/ /pubmed/28334301 http://dx.doi.org/10.1093/bioinformatics/btx141 Text en © The Author 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Notes
Monfort, Matthias
Furlong, Eileen E M
Girardot, Charles
Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets
title Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets
title_full Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets
title_fullStr Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets
title_full_unstemmed Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets
title_short Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets
title_sort dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870560/
https://www.ncbi.nlm.nih.gov/pubmed/28334301
http://dx.doi.org/10.1093/bioinformatics/btx141
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