Modelling haplotypes with respect to reference cohort variation graphs

MOTIVATION: Current statistical models of haplotypes are limited to panels of haplotypes whose genetic variation can be represented by arrays of values at linearly ordered bi- or multiallelic loci. These methods cannot model structural variants or variants that nest or overlap. RESULTS: A variation...

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Detalles Bibliográficos
Autores principales: Rosen, Yohei, Eizenga, Jordan, Paten, Benedict
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Ismb/Eccb 2017: The 25th Annual Conference Intelligent Systems for Molecular Biology Held Jointly with the 16th Annual European Conference on Computational Biology, Prague, Czech Republic, July 21–25, 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870562/
https://www.ncbi.nlm.nih.gov/pubmed/28881971
http://dx.doi.org/10.1093/bioinformatics/btx236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870562/
https://www.ncbi.nlm.nih.gov/pubmed/28881971
http://dx.doi.org/10.1093/bioinformatics/btx236

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