Alternative NHEJ pathway proteins as components of MYCN oncogenic activity in human neural crest stem cell differentiation: implications for neuroblastoma initiation

Neuroblastoma is a cancer of neural crest stem cell (NCSC) lineage. Signaling pathways that regulate NCSC differentiation have been implicated in neuroblastoma tumorigenesis. This is exemplified by MYCN oncogene targets that balance proliferation, differentiation, and cell death similarly in normal...

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Detalles Bibliográficos
Autores principales: Newman, Erika A., Chukkapalli, Sahiti, Bashllari, Daniela, Thomas, Tina T., Van Noord, Raelene A., Lawlor, Elizabeth R., Hoenerhoff, Mark J., Opipari, Anthony W., Opipari, Valerie P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870584/
https://www.ncbi.nlm.nih.gov/pubmed/29238067
http://dx.doi.org/10.1038/s41419-017-0004-9

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