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Pyridoxine 5′-phosphate oxidase is a novel therapeutic target and regulated by the TGF-β signalling pathway in epithelial ovarian cancer

Pyridoxine 5′-phosphate oxidase (PNPO) is an enzyme that converts pyridoxine 5′-phosphate into pyridoxal 5′-phosphate (PLP), an active form of vitamin B6 implicated in several types of cancer. However, the role of PNPO and its regulatory mechanism in epithelial ovarian cancer (EOC) are unknown. In t...

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Detalles Bibliográficos
Autores principales:	Zhang, Lingyun, Zhou, Daibing, Guan, Wencai, Ren, Weimin, Sun, Wenwen, Shi, Jimin, Lin, Qunbo, Zhang, Jinguo, Qiao, Tiankui, Ye, Yulong, Wu, Yun, Zhang, Yaning, Zuo, Xulei, Connor, Kristin L, Xu, Guoxiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870590/ https://www.ncbi.nlm.nih.gov/pubmed/29238081 http://dx.doi.org/10.1038/s41419-017-0050-3

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