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ComplexViewer: visualization of curated macromolecular complexes

SUMMARY: Proteins frequently function as parts of complexes, assemblages of multiple proteins and other biomolecules, yet network visualizations usually only show proteins as parts of binary interactions. ComplexViewer visualizes interactions with more than two participants and thereby avoids the ne...

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Detalles Bibliográficos
Autores principales: Combe, Colin W, Sivade, Marine (Dumousseau), Hermjakob, Henning, Heimbach, Joshua, Meldal, Birgit H M, Micklem, Gos, Orchard, Sandra, Rappsilber, Juri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870653/
https://www.ncbi.nlm.nih.gov/pubmed/29036573
http://dx.doi.org/10.1093/bioinformatics/btx497
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author Combe, Colin W
Sivade, Marine (Dumousseau)
Hermjakob, Henning
Heimbach, Joshua
Meldal, Birgit H M
Micklem, Gos
Orchard, Sandra
Rappsilber, Juri
author_facet Combe, Colin W
Sivade, Marine (Dumousseau)
Hermjakob, Henning
Heimbach, Joshua
Meldal, Birgit H M
Micklem, Gos
Orchard, Sandra
Rappsilber, Juri
author_sort Combe, Colin W
collection PubMed
description SUMMARY: Proteins frequently function as parts of complexes, assemblages of multiple proteins and other biomolecules, yet network visualizations usually only show proteins as parts of binary interactions. ComplexViewer visualizes interactions with more than two participants and thereby avoids the need to first expand these into multiple binary interactions. Furthermore, if binding regions between molecules are known then these can be displayed in the context of the larger complex. AVAILABILITY AND IMPLEMENTATION: freely available under Apache version 2 license; EMBL-EBI Complex Portal: http://www.ebi.ac.uk/complexportal; Source code: https://github.com/MICommunity/ComplexViewer; Package: https://www.npmjs.com/package/complexviewer; http://biojs.io/d/complexviewer. Language: JavaScript; Web technology: Scalable Vector Graphics; Libraries: D3.js.
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spelling pubmed-58706532018-04-05 ComplexViewer: visualization of curated macromolecular complexes Combe, Colin W Sivade, Marine (Dumousseau) Hermjakob, Henning Heimbach, Joshua Meldal, Birgit H M Micklem, Gos Orchard, Sandra Rappsilber, Juri Bioinformatics Applications Notes SUMMARY: Proteins frequently function as parts of complexes, assemblages of multiple proteins and other biomolecules, yet network visualizations usually only show proteins as parts of binary interactions. ComplexViewer visualizes interactions with more than two participants and thereby avoids the need to first expand these into multiple binary interactions. Furthermore, if binding regions between molecules are known then these can be displayed in the context of the larger complex. AVAILABILITY AND IMPLEMENTATION: freely available under Apache version 2 license; EMBL-EBI Complex Portal: http://www.ebi.ac.uk/complexportal; Source code: https://github.com/MICommunity/ComplexViewer; Package: https://www.npmjs.com/package/complexviewer; http://biojs.io/d/complexviewer. Language: JavaScript; Web technology: Scalable Vector Graphics; Libraries: D3.js. Oxford University Press 2017-11-15 2017-08-03 /pmc/articles/PMC5870653/ /pubmed/29036573 http://dx.doi.org/10.1093/bioinformatics/btx497 Text en © The Author 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Notes
Combe, Colin W
Sivade, Marine (Dumousseau)
Hermjakob, Henning
Heimbach, Joshua
Meldal, Birgit H M
Micklem, Gos
Orchard, Sandra
Rappsilber, Juri
ComplexViewer: visualization of curated macromolecular complexes
title ComplexViewer: visualization of curated macromolecular complexes
title_full ComplexViewer: visualization of curated macromolecular complexes
title_fullStr ComplexViewer: visualization of curated macromolecular complexes
title_full_unstemmed ComplexViewer: visualization of curated macromolecular complexes
title_short ComplexViewer: visualization of curated macromolecular complexes
title_sort complexviewer: visualization of curated macromolecular complexes
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870653/
https://www.ncbi.nlm.nih.gov/pubmed/29036573
http://dx.doi.org/10.1093/bioinformatics/btx497
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