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ComplexViewer: visualization of curated macromolecular complexes
SUMMARY: Proteins frequently function as parts of complexes, assemblages of multiple proteins and other biomolecules, yet network visualizations usually only show proteins as parts of binary interactions. ComplexViewer visualizes interactions with more than two participants and thereby avoids the ne...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870653/ https://www.ncbi.nlm.nih.gov/pubmed/29036573 http://dx.doi.org/10.1093/bioinformatics/btx497 |
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author | Combe, Colin W Sivade, Marine (Dumousseau) Hermjakob, Henning Heimbach, Joshua Meldal, Birgit H M Micklem, Gos Orchard, Sandra Rappsilber, Juri |
author_facet | Combe, Colin W Sivade, Marine (Dumousseau) Hermjakob, Henning Heimbach, Joshua Meldal, Birgit H M Micklem, Gos Orchard, Sandra Rappsilber, Juri |
author_sort | Combe, Colin W |
collection | PubMed |
description | SUMMARY: Proteins frequently function as parts of complexes, assemblages of multiple proteins and other biomolecules, yet network visualizations usually only show proteins as parts of binary interactions. ComplexViewer visualizes interactions with more than two participants and thereby avoids the need to first expand these into multiple binary interactions. Furthermore, if binding regions between molecules are known then these can be displayed in the context of the larger complex. AVAILABILITY AND IMPLEMENTATION: freely available under Apache version 2 license; EMBL-EBI Complex Portal: http://www.ebi.ac.uk/complexportal; Source code: https://github.com/MICommunity/ComplexViewer; Package: https://www.npmjs.com/package/complexviewer; http://biojs.io/d/complexviewer. Language: JavaScript; Web technology: Scalable Vector Graphics; Libraries: D3.js. |
format | Online Article Text |
id | pubmed-5870653 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-58706532018-04-05 ComplexViewer: visualization of curated macromolecular complexes Combe, Colin W Sivade, Marine (Dumousseau) Hermjakob, Henning Heimbach, Joshua Meldal, Birgit H M Micklem, Gos Orchard, Sandra Rappsilber, Juri Bioinformatics Applications Notes SUMMARY: Proteins frequently function as parts of complexes, assemblages of multiple proteins and other biomolecules, yet network visualizations usually only show proteins as parts of binary interactions. ComplexViewer visualizes interactions with more than two participants and thereby avoids the need to first expand these into multiple binary interactions. Furthermore, if binding regions between molecules are known then these can be displayed in the context of the larger complex. AVAILABILITY AND IMPLEMENTATION: freely available under Apache version 2 license; EMBL-EBI Complex Portal: http://www.ebi.ac.uk/complexportal; Source code: https://github.com/MICommunity/ComplexViewer; Package: https://www.npmjs.com/package/complexviewer; http://biojs.io/d/complexviewer. Language: JavaScript; Web technology: Scalable Vector Graphics; Libraries: D3.js. Oxford University Press 2017-11-15 2017-08-03 /pmc/articles/PMC5870653/ /pubmed/29036573 http://dx.doi.org/10.1093/bioinformatics/btx497 Text en © The Author 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Applications Notes Combe, Colin W Sivade, Marine (Dumousseau) Hermjakob, Henning Heimbach, Joshua Meldal, Birgit H M Micklem, Gos Orchard, Sandra Rappsilber, Juri ComplexViewer: visualization of curated macromolecular complexes |
title | ComplexViewer: visualization of curated macromolecular complexes |
title_full | ComplexViewer: visualization of curated macromolecular complexes |
title_fullStr | ComplexViewer: visualization of curated macromolecular complexes |
title_full_unstemmed | ComplexViewer: visualization of curated macromolecular complexes |
title_short | ComplexViewer: visualization of curated macromolecular complexes |
title_sort | complexviewer: visualization of curated macromolecular complexes |
topic | Applications Notes |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870653/ https://www.ncbi.nlm.nih.gov/pubmed/29036573 http://dx.doi.org/10.1093/bioinformatics/btx497 |
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