miR-342-3p suppresses hepatocellular carcinoma proliferation through inhibition of IGF-1R-mediated Warburg effect

BACKGROUND: Insulin-like growth factor-1 receptor (IGF-1R) is a well-studied oncogenic factor that promotes cell proliferation and energy metabolism and is overexpressed in numerous cancers including hepatocellular carcinoma (HCC). Aerobic glycolysis is a hallmark of cancer, and drugs targeting its...

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Detalles Bibliográficos
Autores principales: Liu, Wenpeng, Kang, Lei, Han, Juqiang, Wang, Yadong, Shen, Chuan, Yan, Zhifeng, Tai, Yanhong, Zhao, Caiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870664/
https://www.ncbi.nlm.nih.gov/pubmed/29615839
http://dx.doi.org/10.2147/OTT.S161586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870664/
https://www.ncbi.nlm.nih.gov/pubmed/29615839
http://dx.doi.org/10.2147/OTT.S161586

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