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Denoising genome-wide histone ChIP-seq with convolutional neural networks
MOTIVATION: Chromatin immune-precipitation sequencing (ChIP-seq) experiments are commonly used to obtain genome-wide profiles of histone modifications associated with different types of functional genomic elements. However, the quality of histone ChIP-seq data is affected by many experimental parame...
Autores principales: | Koh, Pang Wei, Pierson, Emma, Kundaje, Anshul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870713/ https://www.ncbi.nlm.nih.gov/pubmed/28881977 http://dx.doi.org/10.1093/bioinformatics/btx243 |
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