TIN-X: target importance and novelty explorer

MOTIVATION: The increasing amount of peer-reviewed manuscripts requires the development of specific mining tools to facilitate the visual exploration of evidence linking diseases and proteins. RESULTS: We developed TIN-X, the Target Importance and Novelty eXplorer, to visualize the association betwe...

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Autores principales: Cannon, Daniel C, Yang, Jeremy J, Mathias, Stephen L, Ursu, Oleg, Mani, Subramani, Waller, Anna, Schürer, Stephan C, Jensen, Lars Juhl, Sklar, Larry A, Bologa, Cristian G, Oprea, Tudor I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870731/
https://www.ncbi.nlm.nih.gov/pubmed/28398460
http://dx.doi.org/10.1093/bioinformatics/btx200
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author Cannon, Daniel C
Yang, Jeremy J
Mathias, Stephen L
Ursu, Oleg
Mani, Subramani
Waller, Anna
Schürer, Stephan C
Jensen, Lars Juhl
Sklar, Larry A
Bologa, Cristian G
Oprea, Tudor I
author_facet Cannon, Daniel C
Yang, Jeremy J
Mathias, Stephen L
Ursu, Oleg
Mani, Subramani
Waller, Anna
Schürer, Stephan C
Jensen, Lars Juhl
Sklar, Larry A
Bologa, Cristian G
Oprea, Tudor I
author_sort Cannon, Daniel C
collection PubMed
description MOTIVATION: The increasing amount of peer-reviewed manuscripts requires the development of specific mining tools to facilitate the visual exploration of evidence linking diseases and proteins. RESULTS: We developed TIN-X, the Target Importance and Novelty eXplorer, to visualize the association between proteins and diseases, based on text mining data processed from scientific literature. In the current implementation, TIN-X supports exploration of data for G-protein coupled receptors, kinases, ion channels, and nuclear receptors. TIN-X supports browsing and navigating across proteins and diseases based on ontology classes, and displays a scatter plot with two proposed new bibliometric statistics: Importance and Novelty. AVAILABILITY AND IMPLEMENTATION: http://www.newdrugtargets.org
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spelling pubmed-58707312018-04-05 TIN-X: target importance and novelty explorer Cannon, Daniel C Yang, Jeremy J Mathias, Stephen L Ursu, Oleg Mani, Subramani Waller, Anna Schürer, Stephan C Jensen, Lars Juhl Sklar, Larry A Bologa, Cristian G Oprea, Tudor I Bioinformatics Applications Notes MOTIVATION: The increasing amount of peer-reviewed manuscripts requires the development of specific mining tools to facilitate the visual exploration of evidence linking diseases and proteins. RESULTS: We developed TIN-X, the Target Importance and Novelty eXplorer, to visualize the association between proteins and diseases, based on text mining data processed from scientific literature. In the current implementation, TIN-X supports exploration of data for G-protein coupled receptors, kinases, ion channels, and nuclear receptors. TIN-X supports browsing and navigating across proteins and diseases based on ontology classes, and displays a scatter plot with two proposed new bibliometric statistics: Importance and Novelty. AVAILABILITY AND IMPLEMENTATION: http://www.newdrugtargets.org Oxford University Press 2017-08-15 2017-04-07 /pmc/articles/PMC5870731/ /pubmed/28398460 http://dx.doi.org/10.1093/bioinformatics/btx200 Text en © The Author 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Notes
Cannon, Daniel C
Yang, Jeremy J
Mathias, Stephen L
Ursu, Oleg
Mani, Subramani
Waller, Anna
Schürer, Stephan C
Jensen, Lars Juhl
Sklar, Larry A
Bologa, Cristian G
Oprea, Tudor I
TIN-X: target importance and novelty explorer
title TIN-X: target importance and novelty explorer
title_full TIN-X: target importance and novelty explorer
title_fullStr TIN-X: target importance and novelty explorer
title_full_unstemmed TIN-X: target importance and novelty explorer
title_short TIN-X: target importance and novelty explorer
title_sort tin-x: target importance and novelty explorer
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870731/
https://www.ncbi.nlm.nih.gov/pubmed/28398460
http://dx.doi.org/10.1093/bioinformatics/btx200
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