Simulome: a genome sequence and variant simulator

SUMMARY: Simulome provides a powerful and easy to use tool for creating prokaryotic pseudo-genomes. It provides options that can be used in combination to create mutated variants of the simulated genome, which allows for controlled testing of specific genomic conditions. Simulome can be used in comb...

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Detalles Bibliográficos
Autores principales: Price, Adam, Gibas, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870732/
https://www.ncbi.nlm.nih.gov/pubmed/28186240
http://dx.doi.org/10.1093/bioinformatics/btx091
Descripción
Sumario:SUMMARY: Simulome provides a powerful and easy to use tool for creating prokaryotic pseudo-genomes. It provides options that can be used in combination to create mutated variants of the simulated genome, which allows for controlled testing of specific genomic conditions. Simulome can be used in combination with real reads generated from next-generation sequencing platforms, or with simulated reads. AVAILABILITY AND IMPLEMENTATION: Simulome is available for download at https://github.com/price0416/Simulome and is free for use under the MIT license.

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