Simulome: a genome sequence and variant simulator

SUMMARY: Simulome provides a powerful and easy to use tool for creating prokaryotic pseudo-genomes. It provides options that can be used in combination to create mutated variants of the simulated genome, which allows for controlled testing of specific genomic conditions. Simulome can be used in comb...

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Detalles Bibliográficos
Autores principales: Price, Adam, Gibas, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870732/
https://www.ncbi.nlm.nih.gov/pubmed/28186240
http://dx.doi.org/10.1093/bioinformatics/btx091
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author Price, Adam
Gibas, Cynthia
author_facet Price, Adam
Gibas, Cynthia
author_sort Price, Adam
collection PubMed
description SUMMARY: Simulome provides a powerful and easy to use tool for creating prokaryotic pseudo-genomes. It provides options that can be used in combination to create mutated variants of the simulated genome, which allows for controlled testing of specific genomic conditions. Simulome can be used in combination with real reads generated from next-generation sequencing platforms, or with simulated reads. AVAILABILITY AND IMPLEMENTATION: Simulome is available for download at https://github.com/price0416/Simulome and is free for use under the MIT license.
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spelling pubmed-58707322018-04-05 Simulome: a genome sequence and variant simulator Price, Adam Gibas, Cynthia Bioinformatics Applications Notes SUMMARY: Simulome provides a powerful and easy to use tool for creating prokaryotic pseudo-genomes. It provides options that can be used in combination to create mutated variants of the simulated genome, which allows for controlled testing of specific genomic conditions. Simulome can be used in combination with real reads generated from next-generation sequencing platforms, or with simulated reads. AVAILABILITY AND IMPLEMENTATION: Simulome is available for download at https://github.com/price0416/Simulome and is free for use under the MIT license. Oxford University Press 2017-06-15 2017-02-10 /pmc/articles/PMC5870732/ /pubmed/28186240 http://dx.doi.org/10.1093/bioinformatics/btx091 Text en © The Author 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Applications Notes
Price, Adam
Gibas, Cynthia
Simulome: a genome sequence and variant simulator
title Simulome: a genome sequence and variant simulator
title_full Simulome: a genome sequence and variant simulator
title_fullStr Simulome: a genome sequence and variant simulator
title_full_unstemmed Simulome: a genome sequence and variant simulator
title_short Simulome: a genome sequence and variant simulator
title_sort simulome: a genome sequence and variant simulator
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870732/
https://www.ncbi.nlm.nih.gov/pubmed/28186240
http://dx.doi.org/10.1093/bioinformatics/btx091
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