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HaploMerger2: rebuilding both haploid sub-assemblies from high-heterozygosity diploid genome assembly

SUMMARY: De novo assembly is a difficult issue for heterozygous diploid genomes. The advent of high-throughput short-read and long-read sequencing technologies provides both new challenges and potential solutions to the issue. Here, we present HaploMerger2 (HM2), an automated pipeline for rebuilding...

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Detalles Bibliográficos
Autores principales: Huang, Shengfeng, Kang, Mingjing, Xu, Anlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870766/
https://www.ncbi.nlm.nih.gov/pubmed/28407147
http://dx.doi.org/10.1093/bioinformatics/btx220