Reorientation of the Methyl Group in MAs(III) is the Rate-Limiting Step in the ArsM As(III) S-Adenosylmethionine Methyltransferase Reaction

[Image: see text] The most common biotransformation of trivalent inorganic arsenic (As(III)) is methylation to mono-, di-, and trimethylated species. Methylation is catalyzed by As(III) S-adenosylmethionine (SAM) methyltransferase (termed ArsM in microbes and AS3MT in animals). Methylarsenite (MAs(I...

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Detalles Bibliográficos
Autores principales: Packianathan, Charles, Li, Jiaojiao, Kandavelu, Palani, Sankaran, Banumathi, Rosen, Barry P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870839/
https://www.ncbi.nlm.nih.gov/pubmed/29600290
http://dx.doi.org/10.1021/acsomega.8b00197

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