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Orthologue chemical space and its influence on target prediction

MOTIVATION: In silico approaches often fail to utilize bioactivity data available for orthologous targets due to insufficient evidence highlighting the benefit for such an approach. Deeper investigation into orthologue chemical space and its influence toward expanding compound and target coverage is...

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Detalles Bibliográficos
Autores principales:	Mervin, Lewis H, Bulusu, Krishna C, Kalash, Leen, Afzal, Avid M, Svensson, Fredrik, Firth, Mike A, Barrett, Ian, Engkvist, Ola, Bender, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870859/ https://www.ncbi.nlm.nih.gov/pubmed/28961699 http://dx.doi.org/10.1093/bioinformatics/btx525

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