Reliability of algorithmic somatic copy number alteration detection from targeted capture data

MOTIVATION: Whole exome and gene panel sequencing are increasingly used for oncological diagnostics. To investigate the accuracy of SCNA detection algorithms on simulated and clinical tumor samples, the precision and sensitivity of four SCNA callers were measured using 50 simulated whole exome and 5...

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Detalles Bibliográficos
Autores principales: Rieber, Nora, Bohnert, Regina, Ziehm, Ulrike, Jansen, Gunther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870863/
https://www.ncbi.nlm.nih.gov/pubmed/28472276
http://dx.doi.org/10.1093/bioinformatics/btx284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870863/
https://www.ncbi.nlm.nih.gov/pubmed/28472276
http://dx.doi.org/10.1093/bioinformatics/btx284

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