Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques

BACKGROUND: Despite repeated outbreaks, in particular the devastating 2014–2016 epidemic, there is no effective treatment validated for patients with Ebola virus disease (EVD). Among the drug candidates is the broad-spectrum polymerase inhibitor favipiravir, which showed a good tolerance profile in...

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Detalles Bibliográficos
Autores principales: Guedj, Jérémie, Piorkowski, Géraldine, Jacquot, Frédéric, Madelain, Vincent, Nguyen, Thi Huyen Tram, Rodallec, Anne, Gunther, Stephan, Carbonnelle, Caroline, Mentré, France, Raoul, Hervé, de Lamballerie, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870946/
https://www.ncbi.nlm.nih.gov/pubmed/29584730
http://dx.doi.org/10.1371/journal.pmed.1002535

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