Cargando…

Long-term delivery of brain-derived neurotrophic factor (BDNF) from nanoporous silica nanoparticles improves the survival of spiral ganglion neurons in vitro

Sensorineural hearing loss (SNHL) can be overcome by electrical stimulation of spiral ganglion neurons (SGNs) via a cochlear implant (CI). Restricted CI performance results from the spatial gap between the SGNs and the electrode, but the efficacy of CI is also limited by the degeneration of SGNs as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schmidt, Nadeschda, Schulze, Jennifer, Warwas, Dawid P., Ehlert, Nina, Lenarz, Thomas, Warnecke, Athanasia, Behrens, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870973/ https://www.ncbi.nlm.nih.gov/pubmed/29584754 http://dx.doi.org/10.1371/journal.pone.0194778

Ejemplares similares

Potentiation of Brain-Derived Neurotrophic Factor-Induced Protection of Spiral Ganglion Neurons by C3 Exoenzyme/Rho Inhibitor
por: Harre, Jennifer, et al.
Publicado: (2021)

Corrigendum: Potentiation of brain-derived neurotrophic factor-induced protection of spiral ganglion neurons by C3 exoenzyme/Rho inhibitor
por: Harre, Jennifer, et al.
Publicado: (2022)

Coatings of Different Carbon Nanotubes on Platinum Electrodes for Neuronal Devices: Preparation, Cytocompatibility and Interaction with Spiral Ganglion Cells
por: Burblies, Niklas, et al.
Publicado: (2016)

Phosphodiesterase Type 4 Inhibitor Rolipram Improves Survival of Spiral Ganglion Neurons In Vitro
por: Kranz, Katharina, et al.
Publicado: (2014)

Neuronal Survival, Morphology and Outgrowth of Spiral Ganglion Neurons Using a Defined Growth Factor Combination
por: Schwieger, Jana, et al.
Publicado: (2015)

Biodistribution, biocompatibility and targeted accumulation of magnetic nanoporous silica nanoparticles as drug carrier in orthopedics
por: Janßen, Hilke Catherina, et al.
Publicado: (2020)

In vitro and in vivo accumulation of magnetic nanoporous silica nanoparticles on implant materials with different magnetic properties
por: Janßen, Hilke Catherina, et al.
Publicado: (2018)

Development of Neuronal Guidance Fibers for Stimulating Electrodes: Basic Construction and Delivery of a Growth Factor
por: Wille, Inga, et al.
Publicado: (2022)

Purification of Fibroblasts From the Spiral Ganglion
por: Anacker, Annett, et al.
Publicado: (2022)

Effect of Immunophilin Inhibitors on Cochlear Fibroblasts and Spiral Ganglion Cells
por: Goblet, Madeleine, et al.
Publicado: (2023)

Effect of hyperbaric oxygen on BDNF-release and neuroprotection: Investigations with human mesenchymal stem cells and genetically modified NIH3T3 fibroblasts as putative cell therapeutics
por: Schulze, Jennifer, et al.
Publicado: (2017)

Detection of BDNF-Related Proteins in Human Perilymph in Patients With Hearing Loss
por: de Vries, Ines, et al.
Publicado: (2019)

The Three-Dimensional Culture System with Matrigel and Neurotrophic Factors Preserves the Structure and Function of Spiral Ganglion Neuron In Vitro
por: Sun, Gaoying, et al.
Publicado: (2016)

Functional Pattern of Increasing Concentrations of Brain-Derived Neurotrophic Factor in Spiral Ganglion: Implications for Research on Cochlear Implants
por: Ramku, Emina, et al.
Publicado: (2017)

Decellularized equine carotid artery layers as matrix for regenerated neurites of spiral ganglion neurons
por: Yilmaz-Bayraktar, Suheda, et al.
Publicado: (2019)

Enhanced Survival of Spiral Ganglion Cells After Cessation of Treatment with Brain-Derived Neurotrophic Factor in Deafened Guinea Pigs
por: Agterberg, Martijn J. H., et al.
Publicado: (2009)

Preparation and PET/CT imaging of implant directed (68)Ga-labeled magnetic nanoporous silica nanoparticles
por: Polyak, Andras, et al.
Publicado: (2023)

“Of mice and men”: the relevance of Cometin and Erythropoietin origin for its effects on murine spiral ganglion neuron survival and neurite outgrowth in vitro
por: Schwieger, Jana, et al.
Publicado: (2023)

Magnetic Beads Enhance Adhesion of NIH 3T3 Fibroblasts: A Proof-of-Principle In Vitro Study for Implant-Mediated Long-Term Drug Delivery to the Inner Ear
por: Aliuos, Pooyan, et al.
Publicado: (2016)

Chemically induced hypoxia by dimethyloxalylglycine (DMOG)-loaded nanoporous silica nanoparticles supports endothelial tube formation by sustained VEGF release from adipose tissue-derived stem cells
por: Zippusch, Sarah, et al.
Publicado: (2021)

Similarities in the Biophysical Properties of Spiral-Ganglion and Vestibular-Ganglion Neurons in Neonatal Rats
por: Kalluri, Radha
Publicado: (2021)

From Molecular to Nanotechnology Strategies for Delivery of Neurotrophins: Emphasis on Brain-Derived Neurotrophic Factor (BDNF)
por: Géral, Claire, et al.
Publicado: (2013)

Mechanism and Prevention of Spiral Ganglion Neuron Degeneration in the Cochlea
por: Zhang, Li, et al.
Publicado: (2022)

Fluid Behavior in Nanoporous Silica
por: Ok, Salim, et al.
Publicado: (2020)

Comparison of Methods for the Histological Evaluation of Odontocete Spiral Ganglion Cells
por: Ramírez, Tania, et al.
Publicado: (2020)

Generation of a Spiral Ganglion Neuron Degeneration Mouse Model
por: Hu, Zhengqing, et al.
Publicado: (2021)

Association of Plasma Pro-Brain-Derived Neurotrophic Factor (proBDNF)/Mature Brain-Derived Neurotrophic Factor (mBDNF) Levels with BDNF Gene Val66Met Polymorphism in Alcohol Dependence
por: Mo, Min, et al.
Publicado: (2021)

Sustained Effect of Hyaluronic Acid in Subcutaneous Administration to the Cochlear Spiral Ganglion
por: Inagaki, Yozo, et al.
Publicado: (2016)

Spiral Ganglion Neuron Explant Culture and Electrophysiology on Multi Electrode Arrays
por: Hahnewald, Stefan, et al.
Publicado: (2016)

Protective Effect of Edaravone on Glutamate-Induced Neurotoxicity in Spiral Ganglion Neurons
por: Bai, Xiaohui, et al.
Publicado: (2016)

Spiral Ganglion Stem Cells Can Be Propagated and Differentiated Into Neurons and Glia
por: Diensthuber, Marc, et al.
Publicado: (2014)

Comprehensive transcriptome analysis of cochlear spiral ganglion neurons at multiple ages
por: Li, Chao, et al.
Publicado: (2020)

Developmental Changes in Peripherin-eGFP Expression in Spiral Ganglion Neurons
por: Elliott, Karen L., et al.
Publicado: (2021)

Pericytes control vascular stability and auditory spiral ganglion neuron survival
por: Zhang, Yunpei, et al.
Publicado: (2023)

Specification of neuronal subtypes in the spiral ganglion begins prior to birth in the mouse
por: Sanders, Tessa R., et al.
Publicado: (2022)

486 Molecular Mechanisms of Type II Spiral Ganglion Neuron Development
por: George, Deborah Jane, et al.
Publicado: (2023)

Population genetic study of the brain-derived neurotrophic factor (BDNF) gene
por: Petryshen, TL, et al.
Publicado: (2009)

Serum brain-derived neurotrophic factor (BDNF) is not regulated by testosterone in transmen
por: Auer, Matthias K., et al.
Publicado: (2016)

Brain-Derived Neurotrophic Factor (BDNF) Role in Cannabinoid-Mediated Neurogenesis
por: Ferreira, Filipa Fiel, et al.
Publicado: (2018)

Functional analysis of brain derived neurotrophic factor (BDNF) in Huntington’s disease
por: Zhou, Zhike, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_g1fuasjhfa34c9ctr0omith778