Coconut Shell Liquid Smoke Promotes Burn Wound Healing

The aim of this study was to evaluate burn wound healing activity of coconut shell liquid smoke (CS-LS) in a burn wound animal model. Burn wound–induced mice were treated with CS-LS (CS-LS group), povidone iodine 10% (povidone group), or NaCl 0.9% (NaCl group). Application of CS-LS promoted wound co...

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Autores principales: Tarawan, Vita Murniati, Mantilidewi, Kemala Isnainiasih, Dhini, Ika Miqra, Radhiyanti, Putri Teesa, Sutedja, Endang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871157/
https://www.ncbi.nlm.nih.gov/pubmed/27821610
http://dx.doi.org/10.1177/2156587216674313
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author Tarawan, Vita Murniati
Mantilidewi, Kemala Isnainiasih
Dhini, Ika Miqra
Radhiyanti, Putri Teesa
Sutedja, Endang
author_facet Tarawan, Vita Murniati
Mantilidewi, Kemala Isnainiasih
Dhini, Ika Miqra
Radhiyanti, Putri Teesa
Sutedja, Endang
author_sort Tarawan, Vita Murniati
collection PubMed
description The aim of this study was to evaluate burn wound healing activity of coconut shell liquid smoke (CS-LS) in a burn wound animal model. Burn wound–induced mice were treated with CS-LS (CS-LS group), povidone iodine 10% (povidone group), or NaCl 0.9% (NaCl group). Application of CS-LS promoted wound contraction compared to that of the povidone and NaCl groups (P < .05). This study showed a positive correlation between the number of fibroblasts and wound contraction. The number of fibroblasts was highest in the CS-LS group, compared to that of the povidone and NaCl groups (P < .05). In conclusion, CS-LS promotes burn wound healing by one possible mechanism, by increasing the number of fibroblasts. The results indicate that further experimental trials are needed to develop CS-LS as an alternative topical drug for burn wound healing.
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spelling pubmed-58711572018-04-02 Coconut Shell Liquid Smoke Promotes Burn Wound Healing Tarawan, Vita Murniati Mantilidewi, Kemala Isnainiasih Dhini, Ika Miqra Radhiyanti, Putri Teesa Sutedja, Endang J Evid Based Complementary Altern Med Original Articles The aim of this study was to evaluate burn wound healing activity of coconut shell liquid smoke (CS-LS) in a burn wound animal model. Burn wound–induced mice were treated with CS-LS (CS-LS group), povidone iodine 10% (povidone group), or NaCl 0.9% (NaCl group). Application of CS-LS promoted wound contraction compared to that of the povidone and NaCl groups (P < .05). This study showed a positive correlation between the number of fibroblasts and wound contraction. The number of fibroblasts was highest in the CS-LS group, compared to that of the povidone and NaCl groups (P < .05). In conclusion, CS-LS promotes burn wound healing by one possible mechanism, by increasing the number of fibroblasts. The results indicate that further experimental trials are needed to develop CS-LS as an alternative topical drug for burn wound healing. SAGE Publications 2016-11-29 2017-07 /pmc/articles/PMC5871157/ /pubmed/27821610 http://dx.doi.org/10.1177/2156587216674313 Text en © The Author(s) 2016 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Articles
Tarawan, Vita Murniati
Mantilidewi, Kemala Isnainiasih
Dhini, Ika Miqra
Radhiyanti, Putri Teesa
Sutedja, Endang
Coconut Shell Liquid Smoke Promotes Burn Wound Healing
title Coconut Shell Liquid Smoke Promotes Burn Wound Healing
title_full Coconut Shell Liquid Smoke Promotes Burn Wound Healing
title_fullStr Coconut Shell Liquid Smoke Promotes Burn Wound Healing
title_full_unstemmed Coconut Shell Liquid Smoke Promotes Burn Wound Healing
title_short Coconut Shell Liquid Smoke Promotes Burn Wound Healing
title_sort coconut shell liquid smoke promotes burn wound healing
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871157/
https://www.ncbi.nlm.nih.gov/pubmed/27821610
http://dx.doi.org/10.1177/2156587216674313
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AT radhiyantiputriteesa coconutshellliquidsmokepromotesburnwoundhealing
AT sutedjaendang coconutshellliquidsmokepromotesburnwoundhealing

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