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The asymmetrically segregating lncRNA cherub is required for transforming stem cells into malignant cells

Tumor cells display features that are not found in healthy cells. How they become immortal and how their specific features can be exploited to combat tumorigenesis are key questions in tumor biology. Here we describe the long non-coding RNA cherub that is critically required for the development of b...

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Detalles Bibliográficos
Autores principales: Landskron, Lisa, Steinmann, Victoria, Bonnay, Francois, Burkard, Thomas R, Steinmann, Jonas, Reichardt, Ilka, Harzer, Heike, Laurenson, Anne-Sophie, Reichert, Heinrich, Knoblich, Jürgen A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871330/
https://www.ncbi.nlm.nih.gov/pubmed/29580384
http://dx.doi.org/10.7554/eLife.31347