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Leprosy and American cutaneous leishmaniasis coinfection

Brazil is a country with a high prevalence of infectious diseases such as leprosy and leishmaniasis. However, coinfection of these diseases is still poorly understood. We report a case of a patient who presented with lepromatous leprosy and cutaneous-mucosal leishmaniasis at the same period. After c...

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Autores principales: Mercadante, Larissa Mondadori, dos Santos, Marcel Alex Soares, Pegas, Elisangela Samartin, Kadunc, Bogdana Victória
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871378/
https://www.ncbi.nlm.nih.gov/pubmed/29641713
http://dx.doi.org/10.1590/abd1806-4841.20186698
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author Mercadante, Larissa Mondadori
dos Santos, Marcel Alex Soares
Pegas, Elisangela Samartin
Kadunc, Bogdana Victória
author_facet Mercadante, Larissa Mondadori
dos Santos, Marcel Alex Soares
Pegas, Elisangela Samartin
Kadunc, Bogdana Victória
author_sort Mercadante, Larissa Mondadori
collection PubMed
description Brazil is a country with a high prevalence of infectious diseases such as leprosy and leishmaniasis. However, coinfection of these diseases is still poorly understood. We report a case of a patient who presented with lepromatous leprosy and cutaneous-mucosal leishmaniasis at the same period. After clinical, laboratory, and histopathological diagnosis, the treatment was introduced and the patient showed important clinical improvement. He was followed in our outpatient clinic. Both pathologies play an important role in the immune system. Depending on the immune response profile of the host, diseases may present themselves in different ways. In this case, the patient showed a divergent immune response for each disease. We hypothesized that this response is specific for each pathogen.
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spelling pubmed-58713782018-03-29 Leprosy and American cutaneous leishmaniasis coinfection Mercadante, Larissa Mondadori dos Santos, Marcel Alex Soares Pegas, Elisangela Samartin Kadunc, Bogdana Victória An Bras Dermatol Case Report Brazil is a country with a high prevalence of infectious diseases such as leprosy and leishmaniasis. However, coinfection of these diseases is still poorly understood. We report a case of a patient who presented with lepromatous leprosy and cutaneous-mucosal leishmaniasis at the same period. After clinical, laboratory, and histopathological diagnosis, the treatment was introduced and the patient showed important clinical improvement. He was followed in our outpatient clinic. Both pathologies play an important role in the immune system. Depending on the immune response profile of the host, diseases may present themselves in different ways. In this case, the patient showed a divergent immune response for each disease. We hypothesized that this response is specific for each pathogen. Sociedade Brasileira de Dermatologia 2018 /pmc/articles/PMC5871378/ /pubmed/29641713 http://dx.doi.org/10.1590/abd1806-4841.20186698 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivative License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited and the work is not changed in any way.
spellingShingle Case Report
Mercadante, Larissa Mondadori
dos Santos, Marcel Alex Soares
Pegas, Elisangela Samartin
Kadunc, Bogdana Victória
Leprosy and American cutaneous leishmaniasis coinfection
title Leprosy and American cutaneous leishmaniasis coinfection
title_full Leprosy and American cutaneous leishmaniasis coinfection
title_fullStr Leprosy and American cutaneous leishmaniasis coinfection
title_full_unstemmed Leprosy and American cutaneous leishmaniasis coinfection
title_short Leprosy and American cutaneous leishmaniasis coinfection
title_sort leprosy and american cutaneous leishmaniasis coinfection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871378/
https://www.ncbi.nlm.nih.gov/pubmed/29641713
http://dx.doi.org/10.1590/abd1806-4841.20186698
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