Cargando…

Effects of the Positive Allosteric Modulator of Metabotropic Glutamate Receptor 5, VU-29, on Impairment of Novel Object Recognition Induced by Acute Ethanol and Ethanol Withdrawal in Rats

Glutamate is essential for learning and memory processes, and acute and chronic exposures to ethanol (or protracted abstinence) alter glutamatergic transmission. In the current study, we investigated the effects of VU-29, positive allosteric modulator of metabotropic glutamate 5 (mGlu5) receptor, on...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marszalek-Grabska, Marta, Gibula-Bruzda, Ewa, Bodzon-Kulakowska, Anna, Suder, Piotr, Gawel, Kinga, Filarowska, Joanna, Listos, Joanna, Danysz, Wojciech, Kotlinska, Jolanta H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871646/ https://www.ncbi.nlm.nih.gov/pubmed/29294238 http://dx.doi.org/10.1007/s12640-017-9857-z

Ejemplares similares

Effects of the Positive Allosteric Modulator of Metabotropic Glutamate Receptor 5, VU-29, on Maintenance Association between Environmental Cues and Rewarding Properties of Ethanol in Rats
por: Marszalek-Grabska, Marta, et al.
Publicado: (2020)

Cholinesterase inhibitors, donepezil and rivastigmine, attenuate spatial memory and cognitive flexibility impairment induced by acute ethanol in the Barnes maze task in rats
por: Gawel, Kinga, et al.
Publicado: (2016)

Assessment of spatial learning and memory in the Barnes maze task in rodents—methodological consideration
por: Gawel, Kinga, et al.
Publicado: (2018)

Rapamycin Improves Spatial Learning Deficits, Vulnerability to Alcohol Addiction and Altered Expression of the GluN2B Subunit of the NMDA Receptor in Adult Rats Exposed to Ethanol during the Neonatal Period
por: Lopatynska-Mazurek, Malgorzata, et al.
Publicado: (2021)

Alteration of Ethanol Reward by Prior Mephedrone Exposure: The Role of Age and Matrix Metalloproteinase-9 (MMP-9)
por: Grochecki, Pawel, et al.
Publicado: (2022)

Maternal Separation Alters Ethanol Drinking and Reversal Learning Processes in Adolescent Rats: The Impact of Sex and Glycine Transporter Type 1 (GlyT1) Inhibitor
por: Filarowska-Jurko, Joanna, et al.
Publicado: (2022)

Linagliptin, a Selective Dipeptidyl Peptidase-4 Inhibitor, Reduces Physical and Behavioral Effects of Morphine Withdrawal
por: Listos, Joanna, et al.
Publicado: (2022)

Impact of Mephedrone on Fear Memory in Adolescent Rats: Involvement of Matrix Metalloproteinase-9 (MMP-9) and N-Methyl-D-aspartate (NMDA) Receptor
por: Grochecki, Pawel, et al.
Publicado: (2023)

Identification of Positive Allosteric Modulators VU0155094 (ML397) and VU0422288 (ML396) Reveals New Insights into the Biology of Metabotropic Glutamate Receptor 7
por: Jalan-Sakrikar, Nidhi, et al.
Publicado: (2014)

Constant activity of glutamine synthetase after morphine administration versus proteomic results
por: Bodzon-Kulakowska, Anna, et al.
Publicado: (2010)

The Study of Derivatization Prior MALDI MSI Analysis—Charge Tagging Based on the Cholesterol and Betaine Aldehyde
por: Mielczarek, Przemyslaw, et al.
Publicado: (2021)

Memantine Prevents the WIN 55,212-2 Evoked Cross-Priming of Ethanol-Induced Conditioned Place Preference (CPP)
por: Marszalek-Grabska, Marta, et al.
Publicado: (2021)

Deleterious Effects of Ethanol, Δ(9)-Tetrahydrocannabinol (THC), and Their Combination on the Spatial Memory and Cognitive Flexibility in Adolescent and Adult Male Rats in the Barnes Maze Task
por: Gibula-Tarlowska, Ewa, et al.
Publicado: (2020)

NMDA Receptors and NO:cGMP Signaling Pathway Mediate the Diazepam-Induced Sensitization to Withdrawal Signs in Mice
por: Talarek, Sylwia, et al.
Publicado: (2017)

DESI–MS as a tool for direct lipid analysis in cultured cells
por: Bodzon-Kulakowska, Anna, et al.
Publicado: (2014)

Effects of Mephedrone and Amphetamine Exposure during Adolescence on Spatial Memory in Adulthood: Behavioral and Neurochemical Analysis
por: Grochecki, Pawel, et al.
Publicado: (2021)

Allosteric Molecular Switches in Metabotropic Glutamate Receptors
por: Orgován, Zoltán, et al.
Publicado: (2020)

Mouse single oocyte imaging by MALDI-TOF MS for lipidomics
por: Bodzon-Kulakowska, Anna, et al.
Publicado: (2020)

Mass Spectrometry Imaging of Biomaterials
por: Kret, Paulina, et al.
Publicado: (2023)

Oscillatory Deficits in the Sub-Chronic PCP Rat Model for Schizophrenia Are Reversed by mGlu5 Receptor-Positive Allosteric Modulators VU0409551 and VU0360172
por: Brown, Jessica, et al.
Publicado: (2023)

Rapamycin Improves Recognition Memory and Normalizes Amino-Acids and Amines Levels in the Hippocampal Dentate Gyrus in Adult Rats Exposed to Ethanol during the Neonatal Period
por: Lopatynska-Mazurek, Malgorzata, et al.
Publicado: (2021)

Neonatal Maternal Separation Induces Sexual Dimorphism in Brain Development: The Influence on Amino Acid Levels and Cognitive Disorders
por: Kotlinska, Jolanta H., et al.
Publicado: (2023)

A comparative study of glycoproteomes in androgen-sensitive and -independent prostate cancer cell lines
por: Drabik, Anna, et al.
Publicado: (2013)

Erratum to: A comparative study of glycoproteomes in androgen-sensitive and -independent prostate cancer cell lines
por: Drabik, Anna, et al.
Publicado: (2014)

Conformational fingerprinting of allosteric modulators in metabotropic glutamate receptor 2
por: Liauw, Brandon Wey-Hung, et al.
Publicado: (2022)

Fenofibrate (a PPAR-α Agonist) Administered During Ethanol Withdrawal Reverts Ethanol-Induced Astrogliosis and Restores the Levels of Glutamate Transporter in Ethanol-Administered Adolescent Rats
por: Villavicencio-Tejo, Francisca, et al.
Publicado: (2021)

Allosteric Modulators of Metabotropic Glutamate Receptors as Novel Therapeutics for Neuropsychiatric Disease
por: Luessen, Deborah J., et al.
Publicado: (2022)

Clavulanic acid improves ethanol withdrawal symptoms in rats
por: Mohebbi, Ehsan, et al.
Publicado: (2020)

Mammalian Oocyte Analysis by MALDI MSI with Wet-Interface Matrix Deposition Technique
por: Bodzon-Kulakowska, Anna, et al.
Publicado: (2023)

A Novel Sulfonamide, 4-FS, Reduces Ethanol Drinking and Physical Withdrawal Associated With Ethanol Dependence
por: Sona Khan, Muhammad, et al.
Publicado: (2020)

Identification of Allosteric Modulators of Metabotropic Glutamate 7 Receptor Using Proteochemometric Modeling
por: Tresadern, Gary, et al.
Publicado: (2017)

Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5
por: Kampen, Stefanie, et al.
Publicado: (2022)

Discovery of N-(5-Fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide (VU0424238): A Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Selected for Clinical Evaluation
por: Felts, Andrew S., et al.
Publicado: (2017)

Developmental Exposure to Kynurenine Affects Zebrafish and Rat Behavior
por: Marszalek-Grabska, Marta, et al.
Publicado: (2023)

Preferential binding of allosteric modulators to active and inactive conformational states of metabotropic glutamate receptors
por: Yanamala, Naveena, et al.
Publicado: (2008)

Covalent Allosteric Probe for the Metabotropic Glutamate Receptor 2: Design, Synthesis, and Pharmacological Characterization
por: Doornbos, Maarten L. J., et al.
Publicado: (2018)

Conformational dynamics between transmembrane domains and allosteric modulation of a metabotropic glutamate receptor
por: Gutzeit, Vanessa A, et al.
Publicado: (2019)

Dejà Vu
por: Artinian, Boghos L.
Publicado: (2003)

Déjà vu!
por: Chate, R.
Publicado: (2020)

Effect of Histone Deacetylase Inhibitor on Ethanol Withdrawal-Induced Hyperalgesia in Rats
por: Pradhan, Amynah A, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_trq8fcj5oitu1pr763oci2r5ju