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Extracellular NGFR Spacers Allow Efficient Tracking and Enrichment of Fully Functional CAR-T Cells Co-Expressing a Suicide Gene
Chimeric antigen receptor (CAR)-T cell immunotherapy is at the forefront of innovative cancer therapeutics. However, lack of standardization of cellular products within the same clinical trial and lack of harmonization between different trials have hindered the clear identification of efficacy and s...
Autores principales: | Casucci, Monica, Falcone, Laura, Camisa, Barbara, Norelli, Margherita, Porcellini, Simona, Stornaiuolo, Anna, Ciceri, Fabio, Traversari, Catia, Bordignon, Claudio, Bonini, Chiara, Bondanza, Attilio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871667/ https://www.ncbi.nlm.nih.gov/pubmed/29619024 http://dx.doi.org/10.3389/fimmu.2018.00507 |
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