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Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC
Axon guidance involves the spatiotemporal interplay between guidance cues and membrane-bound cell-surface receptors, present on the growth cone of the axon. Netrin-1 is a prototypical guidance cue that binds to deleted in colorectal cancer (DCC), and it has been proposed that the guidance cue Draxin...
Autores principales: | Liu, Ying, Bhowmick, Tuhin, Liu, Yiqiong, Gao, Xuefan, Mertens, Haydyn D.T., Svergun, Dmitri I., Xiao, Junyu, Zhang, Yan, Wang, Jia-huai, Meijers, Rob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871715/ https://www.ncbi.nlm.nih.gov/pubmed/29503192 http://dx.doi.org/10.1016/j.neuron.2018.02.010 |
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