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Dexras1 is a homeostatic regulator of exercise-dependent proliferation and cell survival in the hippocampal neurogenic niche

Adult hippocampal neurogenesis is highly responsive to exercise, which promotes the proliferation of neural progenitor cells and the integration of newborn granule neurons in the dentate gyrus. Here we show that genetic ablation of the small GTPase, Dexras1, suppresses exercise-induced proliferation...

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Detalles Bibliográficos
Autores principales: Bouchard-Cannon, Pascale, Lowden, Christopher, Trinh, Dennison, Cheng, Hai-Ying M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871767/
https://www.ncbi.nlm.nih.gov/pubmed/29593295
http://dx.doi.org/10.1038/s41598-018-23673-z