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Sample-Index Misassignment Impacts Tumour Exome Sequencing
Sample pooling enabled by dedicated indexes is a common strategy for cost-effective and robust high-throughput sequencing. Index misassignment leading to mutual contamination between pooled samples has however been described as a general problem of the latest Illumina sequencing instruments utilizin...
Autores principales: | Vodák, Daniel, Lorenz, Susanne, Nakken, Sigve, Aasheim, Lars Birger, Holte, Harald, Bai, Baoyan, Myklebost, Ola, Meza-Zepeda, Leonardo A., Hovig, Eivind |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871786/ https://www.ncbi.nlm.nih.gov/pubmed/29593270 http://dx.doi.org/10.1038/s41598-018-23563-4 |
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