LepVax, a defined subunit vaccine that provides effective pre-exposure and post-exposure prophylaxis of M. leprae infection

Sustained elimination of leprosy as a global health concern likely requires a vaccine. The current standard, BCG, confers only partial protection and precipitates paucibacillary (PB) disease in some instances. When injected into mice with the T helper 1 (Th1)-biasing adjuvant formulation Glucopyrano...

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Detalles Bibliográficos
Autores principales: Duthie, Malcolm S., Pena, Maria T., Ebenezer, Gigi J., Gillis, Thomas P., Sharma, Rahul, Cunningham, Kelly, Polydefkis, Michael, Maeda, Yumi, Makino, Masahiko, Truman, Richard W., Reed, Steven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871809/
https://www.ncbi.nlm.nih.gov/pubmed/29619252
http://dx.doi.org/10.1038/s41541-018-0050-z

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