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Structural insights into the RNA methyltransferase domain of METTL16

N(6)-methyladenosine (m(6)A) is an abundant modification in messenger RNA and noncoding RNAs that affects RNA metabolism. Methyltransferase-like protein 16 (METTL16) is a recently confirmed m(6)A RNA methyltransferase that methylates U6 spliceosomal RNA and interacts with the 3′-terminal RNA triple...

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Detalles Bibliográficos
Autores principales:	Ruszkowska, Agnieszka, Ruszkowski, Milosz, Dauter, Zbigniew, Brown, Jessica A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871880/ https://www.ncbi.nlm.nih.gov/pubmed/29593291 http://dx.doi.org/10.1038/s41598-018-23608-8

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