Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion

A chronic viral or tumor microenvironment can push T cells to exhaustion by promoting coinhibitory ligand expression. However, how host factors control coinhibitory ligand expression and whether viral infection breaks this control during tumor progress is unknown. Here we show a close negative corre...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Cheng, Lan, Peixiang, Han, Qiuju, Huang, Mei, Zhang, Zhihong, Xu, Geliang, Song, Jiaxi, Wang, Jinyu, Wei, Haiming, Zhang, Jian, Sun, Rui, Zhang, Cai, Tian, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871883/
https://www.ncbi.nlm.nih.gov/pubmed/29593314
http://dx.doi.org/10.1038/s41467-018-03584-3

Ejemplares similares

Ejemplares similares