Cargando…

Decreased ATP production and myocardial contractile reserve in metabolic heart disease

Metabolic syndrome is a cluster of obesity-related metabolic abnormalities that lead to metabolic heart disease (MHD) with left ventricular pump dysfunction. Although MHD is thought to be associated with myocardial energetic deficiency, two key questions have not been answered. First, it is not know...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luptak, Ivan, Sverdlov, Aaron L., Panagia, Marcello, Qin, Fuzhong, Pimentel, David R., Croteau, Dominique, Siwik, Deborah A., Ingwall, Joanne S., Bachschmid, Markus M., Balschi, James A., Colucci, Wilson S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871926/ https://www.ncbi.nlm.nih.gov/pubmed/29409987 http://dx.doi.org/10.1016/j.yjmcc.2018.01.017

Ejemplares similares

SGLT2 inhibitor ertugliflozin decreases elevated intracellular sodium, and improves energetics and contractile function in diabetic cardiomyopathy
por: Croteau, Dominique, et al.
Publicado: (2023)

Differential Effects of Sacubitril/Valsartan on Diastolic Function in Mice With Obesity-Related Metabolic Heart Disease
por: Croteau, Dominique, et al.
Publicado: (2020)

Effects of Sodium‐Glucose Linked Transporter 2 Inhibition With Ertugliflozin on Mitochondrial Function, Energetics, and Metabolic Gene Expression in the Presence and Absence of Diabetes Mellitus in Mice
por: Croteau, Dominique, et al.
Publicado: (2021)

A novel tracer for in vivo optical imaging of fatty acid metabolism in the heart and brown adipose tissue
por: Panagia, Marcello, et al.
Publicado: (2020)

Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet‐Induced Metabolic Heart Disease
por: Sverdlov, Aaron L., et al.
Publicado: (2016)

Partial Liver Kinase B1 (LKB1) Deficiency Promotes Diastolic Dysfunction, De Novo Systolic Dysfunction, Apoptosis, and Mitochondrial Dysfunction With Dietary Metabolic Challenge
por: Miller, Edward J., et al.
Publicado: (2015)

Galectin‐3 Is Associated With Stage B Metabolic Heart Disease and Pulmonary Hypertension in Young Obese Patients
por: Gopal, Deepa M., et al.
Publicado: (2019)

Metabolic Syndrome and Myocardial Contractile Reserve
por: Kim, Seong Hwan
Publicado: (2011)

Hydrogen Peroxide–Mediated SERCA Cysteine 674 Oxidation Contributes to Impaired Cardiac Myocyte Relaxation in Senescent Mouse Heart
por: Qin, Fuzhong, et al.
Publicado: (2013)

Overexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins
por: Yao, Chunxiang, et al.
Publicado: (2015)

Novel Small-Molecule Troponin Activator Increases Cardiac Contractile Function Without Negative Impact on Energetics
por: He, Huamei, et al.
Publicado: (2021)

Contractile Reserve in Heart Failure with Preserved Ejection Fraction
por: Di Lisi, Daniela, et al.
Publicado: (2022)

Impact of contractile reserve on acute response to cardiac resynchronization therapy
por: Moonen, Marie, et al.
Publicado: (2008)

Cardiac Contractile Reserve Parameters Are Related to Prognosis in Septic Shock
por: Kimmoun, Antoine, et al.
Publicado: (2013)

The Significance of “Contractile Reserve” in the Echocardiographic Assessment of Athletic Heart Syndrome
por: Christopoulos, Georgios, et al.
Publicado: (2020)

The Effect of Metabolic Syndrome on Myocardial Contractile Reserve during Exercise in Non-Diabetic Hypertensive Subjects
por: Ha, Tae Hoon, et al.
Publicado: (2011)

Right ventriculo–arterial uncoupling and impaired contractile reserve in obese patients with unexplained exercise intolerance
por: McCabe, Colm, et al.
Publicado: (2018)

Myocardial perfusion reserve and contractile pattern after beta-blocker therapy in patients with idiopathic dilated cardiomyopathy
por: Slart, R. H. J. A., et al.
Publicado: (2010)

Integrated wall stress: a new methodological approach to assess ventricular workload and myocardial contractile reserve
por: Dong, Hailong, et al.
Publicado: (2013)

Childhood Cancer Survivors Have Impaired Strain-Derived Myocardial Contractile Reserve by Dobutamine Stress Echocardiography
por: Broberg, Olof, et al.
Publicado: (2023)

Early impairment of contractility reserve in patients with insulin resistance in comparison with healthy subjects
por: Cadeddu, Christian, et al.
Publicado: (2013)

Role of Glutaredoxin-1 and Glutathionylation in Cardiovascular Diseases
por: Burns, Mannix, et al.
Publicado: (2020)

Potential Role of Extracellular ATP Released by Bacteria in Bladder Infection and Contractility
por: Abbasian, Behnam, et al.
Publicado: (2019)

Echocardiographic Normal Reference of Left Ventricular Contractile Reserve During Treadmill Exercise Stress Echocardiography in Healthy Chinese Adults – New Non-Sex-Specific Parameter for Left Ventricular Contractile Reserve Evaluation
por: Wang, Yi, et al.
Publicado: (2021)

Contractile reserve assessed by dobutamine test identifies super-responders to cardiac resynchronization therapy
por: Vukajlovic, Dejan, et al.
Publicado: (2014)

The importance of contractile reserve in predicting exercise tolerance in asymptomatic patients with severe aortic stenosis
por: van Zalen, Jet, et al.
Publicado: (2019)

Pigment Epithelium‐Derived Factor (PEDF) Improves Ischemic Cardiac Functional Reserve Through Decreasing Hypoxic Cardiomyocyte Contractility Through PEDF Receptor (PEDF‐R)
por: Lu, Peng, et al.
Publicado: (2016)

Increasing carbohydrate oxidation improves contractile reserves and prevents hypertrophy in porcine right heart failure
por: Bøgh, Nikolaj, et al.
Publicado: (2020)

Coronary Flow, Left Ventricular Contractile and Heart Rate Reserve in Non-Ischemic Heart Failure
por: Daros, Clarissa Borguezan, et al.
Publicado: (2021)

Ultrasound-Derived Diaphragm Contractile Reserve as a Marker of Clinical Status in Patients With Cystic Fibrosis
por: Gabrysz-Forget, Fanny, et al.
Publicado: (2022)

Low-flow/low-gradient aortic stenosis without contractile reserve—a case report
por: Stastny, Lukas, et al.
Publicado: (2022)

Increased cardiac contractility by decreased HAX-1 expression
por: Zhao, Wen
Publicado: (2012)

Roles of creatine in the regulation of cardiac protein synthesis
por: Ingwall, JS, et al.
Publicado: (1976)

Removal of urothelium affects bladder contractility and release of ATP but not release of NO in rat urinary bladder
por: Munoz, Alvaro, et al.
Publicado: (2010)

Upregulation of Cardiomyocyte Ribonucleotide Reductase Increases Intracellular 2 deoxy-ATP, Contractility, and Relaxation
por: Korte, F. Steven, et al.
Publicado: (2011)

Overactive ATP-Sensitive K(+) Channels Compromise Lymphatic Contractile Function in Cantú Syndrome
por: Aziz, Qadeer
Publicado: (2023)

Assessment of cardiovascular physiology using magnetic resonance myocardial stress testing reveals impaired contractile reserve in patients with cirrhotic cardiomyopathy
por: Sampaio, Francisco, et al.
Publicado: (2015)

Dynamic Dyssynchrony and Impaired Contractile Reserve of the Left Ventricle in Beta-Thalassaemia Major: An Exercise Echocardiographic Study
por: Cheung, Yiu-fai, et al.
Publicado: (2012)

Clinical and echocardiographic differences in patients with dilated cardiomyopathy in the frame depending preserved left ventricular contractile reserve
por: Peric, V, et al.
Publicado: (2013)

Impact of right ventricular contractile reserve during low‐load exercise on exercise intolerance in heart failure
por: Kinoshita, Masaki, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_i8gjc2hhk283l1dfpaapu3b9bf