Hepatitis B Virus Genotype C is Predominant in Myanmar

Myanmar is adjacent to India, Bangladesh, Thailand, Laos and China. In Myanmar, the prevalence of hepatitis B virus (HBV) infections is 6.5% and accounts for 60% of hepatocellular carcinoma. HBV has nine genotypes that have been identified by molecular genetic analysis. HBV genotypes are associated...

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Autores principales: Nwe Win, Nan, Nakamoto, Shingo, Myint Sein, Myint, Moriyama, Mitsuhiko, Kanda, Tatsuo, Shirasawa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871949/
https://www.ncbi.nlm.nih.gov/pubmed/29278399
http://dx.doi.org/10.3390/diseases6010003
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author Nwe Win, Nan
Nakamoto, Shingo
Myint Sein, Myint
Moriyama, Mitsuhiko
Kanda, Tatsuo
Shirasawa, Hiroshi
author_facet Nwe Win, Nan
Nakamoto, Shingo
Myint Sein, Myint
Moriyama, Mitsuhiko
Kanda, Tatsuo
Shirasawa, Hiroshi
author_sort Nwe Win, Nan
collection PubMed
description Myanmar is adjacent to India, Bangladesh, Thailand, Laos and China. In Myanmar, the prevalence of hepatitis B virus (HBV) infections is 6.5% and accounts for 60% of hepatocellular carcinoma. HBV has nine genotypes that have been identified by molecular genetic analysis. HBV genotypes are associated with several clinical features. We reviewed the prevalence of HBV genotypes in Myanmar and neighboring countries. We also reviewed HBV genotypes in refugees from Myanmar. HBV subgenotype C1 is predominant in Myanmar. As HBV genotype C is associated with hepatocellular carcinoma (HCC), it is important to screen for cirrhosis and HCC and to prevent their development in HBV-infected individuals of Myanmar.
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spelling pubmed-58719492018-03-29 Hepatitis B Virus Genotype C is Predominant in Myanmar Nwe Win, Nan Nakamoto, Shingo Myint Sein, Myint Moriyama, Mitsuhiko Kanda, Tatsuo Shirasawa, Hiroshi Diseases Commentary Myanmar is adjacent to India, Bangladesh, Thailand, Laos and China. In Myanmar, the prevalence of hepatitis B virus (HBV) infections is 6.5% and accounts for 60% of hepatocellular carcinoma. HBV has nine genotypes that have been identified by molecular genetic analysis. HBV genotypes are associated with several clinical features. We reviewed the prevalence of HBV genotypes in Myanmar and neighboring countries. We also reviewed HBV genotypes in refugees from Myanmar. HBV subgenotype C1 is predominant in Myanmar. As HBV genotype C is associated with hepatocellular carcinoma (HCC), it is important to screen for cirrhosis and HCC and to prevent their development in HBV-infected individuals of Myanmar. MDPI 2017-12-26 /pmc/articles/PMC5871949/ /pubmed/29278399 http://dx.doi.org/10.3390/diseases6010003 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Commentary
Nwe Win, Nan
Nakamoto, Shingo
Myint Sein, Myint
Moriyama, Mitsuhiko
Kanda, Tatsuo
Shirasawa, Hiroshi
Hepatitis B Virus Genotype C is Predominant in Myanmar
title Hepatitis B Virus Genotype C is Predominant in Myanmar
title_full Hepatitis B Virus Genotype C is Predominant in Myanmar
title_fullStr Hepatitis B Virus Genotype C is Predominant in Myanmar
title_full_unstemmed Hepatitis B Virus Genotype C is Predominant in Myanmar
title_short Hepatitis B Virus Genotype C is Predominant in Myanmar
title_sort hepatitis b virus genotype c is predominant in myanmar
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871949/
https://www.ncbi.nlm.nih.gov/pubmed/29278399
http://dx.doi.org/10.3390/diseases6010003
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AT kandatatsuo hepatitisbvirusgenotypecispredominantinmyanmar
AT shirasawahiroshi hepatitisbvirusgenotypecispredominantinmyanmar

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