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Fragment-Based Discovery of Inhibitors of the Bacterial DnaG-SSB Interaction

In bacteria, the DnaG primase is responsible for synthesis of short RNA primers used to initiate chain extension by replicative DNA polymerase(s) during chromosomal replication. Among the proteins with which Escherichia coli DnaG interacts is the single-stranded DNA-binding protein, SSB. The C-termi...

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Detalles Bibliográficos
Autores principales:	Chilingaryan, Zorik, Headey, Stephen J., Lo, Allen T. Y., Xu, Zhi-Qiang, Otting, Gottfried, Dixon, Nicholas E., Scanlon, Martin J., Oakley, Aaron J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872125/ https://www.ncbi.nlm.nih.gov/pubmed/29470422 http://dx.doi.org/10.3390/antibiotics7010014

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