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A Novel Polyamine-Targeted Therapy for BRAF Mutant Melanoma Tumors
Mutant serine/threonine protein kinase B-Raf (BRAF) protein is expressed in over half of all melanoma tumors. Although BRAF inhibitors (BRAFi) elicit rapid anti-tumor responses in the majority of patients with mutant BRAF melanoma, the tumors inevitably relapse after a short time. We hypothesized th...
Autores principales: | Peters, Molly C., Minton, Allyson, Phanstiel, Otto, Gilmour, Susan K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872160/ https://www.ncbi.nlm.nih.gov/pubmed/29304009 http://dx.doi.org/10.3390/medsci6010003 |
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