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Autoimmune Diseases and Oral Health: 30-Year Follow-Up of a Swedish Cohort

Oral infections up-regulate a number of systemic inflammatory reactions that, in turn, play a role in the development of systemic diseases. We investigated the association between oral health and autoimmune diseases in a cohort of Swedish adults. Hypothesis was that poor oral health associates with...

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Autores principales: Julkunen, Anna, Heikkinen, Anna Maria, Söder, Birgitta, Söder, Per-Östen, Toppila-Salmi, Sanna, Meurman, Jukka H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872203/
https://www.ncbi.nlm.nih.gov/pubmed/29563402
http://dx.doi.org/10.3390/dj6010001
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author Julkunen, Anna
Heikkinen, Anna Maria
Söder, Birgitta
Söder, Per-Östen
Toppila-Salmi, Sanna
Meurman, Jukka H.
author_facet Julkunen, Anna
Heikkinen, Anna Maria
Söder, Birgitta
Söder, Per-Östen
Toppila-Salmi, Sanna
Meurman, Jukka H.
author_sort Julkunen, Anna
collection PubMed
description Oral infections up-regulate a number of systemic inflammatory reactions that, in turn, play a role in the development of systemic diseases. We investigated the association between oral health and autoimmune diseases in a cohort of Swedish adults. Hypothesis was that poor oral health associates with incidence of autoimmune diseases. Overall 1676 subjects aged 30–40 years old from Stockholm County (Sweden) participated in this study in 1985. Subjects were randomly selected from the registry file of Stockholm region and were followed-up for 30 years. Their hospital and open health care admissions (World Health Organization ICD 9 and 10 codes) were recorded from the Swedish national health registers. The association between the diagnosed autoimmune disease and the oral health variables were statistically analyzed. In all, 50 patients with autoimmune diagnoses were detected from the data. Plaque index was significantly higher in the autoimmune disease group (≥median 35 (70%) vs. ˂median 872 (54%), p = 0.030). No statistical difference was found in gingival index, calculus index, missing teeth, periodontal pockets, smoking or snuff use between patients with and without autoimmune disease. Our study hypothesis was partly confirmed. The result showed that subjects with a higher plaque index, marker of poor oral hygiene, were more likely to develop autoimmune diseases in 30 years.
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spelling pubmed-58722032018-03-29 Autoimmune Diseases and Oral Health: 30-Year Follow-Up of a Swedish Cohort Julkunen, Anna Heikkinen, Anna Maria Söder, Birgitta Söder, Per-Östen Toppila-Salmi, Sanna Meurman, Jukka H. Dent J (Basel) Article Oral infections up-regulate a number of systemic inflammatory reactions that, in turn, play a role in the development of systemic diseases. We investigated the association between oral health and autoimmune diseases in a cohort of Swedish adults. Hypothesis was that poor oral health associates with incidence of autoimmune diseases. Overall 1676 subjects aged 30–40 years old from Stockholm County (Sweden) participated in this study in 1985. Subjects were randomly selected from the registry file of Stockholm region and were followed-up for 30 years. Their hospital and open health care admissions (World Health Organization ICD 9 and 10 codes) were recorded from the Swedish national health registers. The association between the diagnosed autoimmune disease and the oral health variables were statistically analyzed. In all, 50 patients with autoimmune diagnoses were detected from the data. Plaque index was significantly higher in the autoimmune disease group (≥median 35 (70%) vs. ˂median 872 (54%), p = 0.030). No statistical difference was found in gingival index, calculus index, missing teeth, periodontal pockets, smoking or snuff use between patients with and without autoimmune disease. Our study hypothesis was partly confirmed. The result showed that subjects with a higher plaque index, marker of poor oral hygiene, were more likely to develop autoimmune diseases in 30 years. MDPI 2017-12-22 /pmc/articles/PMC5872203/ /pubmed/29563402 http://dx.doi.org/10.3390/dj6010001 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Julkunen, Anna
Heikkinen, Anna Maria
Söder, Birgitta
Söder, Per-Östen
Toppila-Salmi, Sanna
Meurman, Jukka H.
Autoimmune Diseases and Oral Health: 30-Year Follow-Up of a Swedish Cohort
title Autoimmune Diseases and Oral Health: 30-Year Follow-Up of a Swedish Cohort
title_full Autoimmune Diseases and Oral Health: 30-Year Follow-Up of a Swedish Cohort
title_fullStr Autoimmune Diseases and Oral Health: 30-Year Follow-Up of a Swedish Cohort
title_full_unstemmed Autoimmune Diseases and Oral Health: 30-Year Follow-Up of a Swedish Cohort
title_short Autoimmune Diseases and Oral Health: 30-Year Follow-Up of a Swedish Cohort
title_sort autoimmune diseases and oral health: 30-year follow-up of a swedish cohort
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872203/
https://www.ncbi.nlm.nih.gov/pubmed/29563402
http://dx.doi.org/10.3390/dj6010001
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