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The Hypoxia-Mimetic Agent Cobalt Chloride Differently Affects Human Mesenchymal Stem Cells in Their Chondrogenic Potential
Adult stem cells are a promising cell source for cartilage regeneration. They resided in a special microenvironment known as the stem-cell niche, characterized by the presence of low oxygen concentration. Cobalt chloride (CoCl(2)) imitates hypoxia in vitro by stabilizing hypoxia-inducible factor-alp...
Autores principales: | Teti, Gabriella, Focaroli, Stefano, Salvatore, Viviana, Mazzotti, Eleonora, Ingra', Laura, Mazzotti, Antonio, Falconi, Mirella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872594/ https://www.ncbi.nlm.nih.gov/pubmed/29731777 http://dx.doi.org/10.1155/2018/3237253 |
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