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Periconceptional Folic Acid Supplementation Benefit to Development of Early Sensory-Motor Function through Increase DNA Methylation in Rat Offspring

Periconceptional maternal folate levels may alter DNA methylation patterns and health outcomes in offspring. We hypothesized that maternal folic acid supplementation alters fetal neural development through DNA methylation in the fetal brain. Twenty-eight rats were randomly assigned to four groups: t...

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Detalles Bibliográficos
Autores principales: Li, Wen, Li, Zhenshu, Li, Shou, Wang, Xinyan, Wilson, John X., Huang, Guowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872710/
https://www.ncbi.nlm.nih.gov/pubmed/29494536
http://dx.doi.org/10.3390/nu10030292