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Carboxylic Terminated Thermo-Responsive Copolymer Hydrogel and Improvement in Peptide Release Profile
To improve the release profile of peptide drugs, thermos-responsive triblock copolymer poly (ε-caprolactone-co-p-dioxanone)-b-poly (ethylene glycol)-b-poly (ε-caprolactone-co-p-dioxanone) (PECP) was prepared and end capped by succinic anhydride to give its carboxylic terminated derivative. Both PCEP...
Autores principales: | Rao, Zi-Kun, Chen, Rui, Zhu, Hong-Yu, Li, Yang, Liu, Yu, Hao, Jian-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872917/ https://www.ncbi.nlm.nih.gov/pubmed/29495382 http://dx.doi.org/10.3390/ma11030338 |
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