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Bioactive Glass-Ceramic Foam Scaffolds from ‘Inorganic Gel Casting’ and Sinter-Crystallization

Highly porous bioactive glass-ceramic scaffolds were effectively fabricated by an inorganic gel casting technique, based on alkali activation and gelification, followed by viscous flow sintering. Glass powders, already known to yield a bioactive sintered glass-ceramic (CEL2) were dispersed in an alk...

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Autores principales: Elsayed, Hamada, Rincón Romero, Acacio, Molino, Giulia, Vitale Brovarone, Chiara, Bernardo, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872928/
https://www.ncbi.nlm.nih.gov/pubmed/29495498
http://dx.doi.org/10.3390/ma11030349
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author Elsayed, Hamada
Rincón Romero, Acacio
Molino, Giulia
Vitale Brovarone, Chiara
Bernardo, Enrico
author_facet Elsayed, Hamada
Rincón Romero, Acacio
Molino, Giulia
Vitale Brovarone, Chiara
Bernardo, Enrico
author_sort Elsayed, Hamada
collection PubMed
description Highly porous bioactive glass-ceramic scaffolds were effectively fabricated by an inorganic gel casting technique, based on alkali activation and gelification, followed by viscous flow sintering. Glass powders, already known to yield a bioactive sintered glass-ceramic (CEL2) were dispersed in an alkaline solution, with partial dissolution of glass powders. The obtained glass suspensions underwent progressive hardening, by curing at low temperature (40 °C), owing to the formation of a C–S–H (calcium silicate hydrate) gel. As successful direct foaming was achieved by vigorous mechanical stirring of gelified suspensions, comprising also a surfactant. The developed cellular structures were later heat-treated at 900–1000 °C, to form CEL2 glass-ceramic foams, featuring an abundant total porosity (from 60% to 80%) and well-interconnected macro- and micro-sized cells. The developed foams possessed a compressive strength from 2.5 to 5 MPa, which is in the range of human trabecular bone strength. Therefore, CEL2 glass-ceramics can be proposed for bone substitutions.
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spelling pubmed-58729282018-03-30 Bioactive Glass-Ceramic Foam Scaffolds from ‘Inorganic Gel Casting’ and Sinter-Crystallization Elsayed, Hamada Rincón Romero, Acacio Molino, Giulia Vitale Brovarone, Chiara Bernardo, Enrico Materials (Basel) Article Highly porous bioactive glass-ceramic scaffolds were effectively fabricated by an inorganic gel casting technique, based on alkali activation and gelification, followed by viscous flow sintering. Glass powders, already known to yield a bioactive sintered glass-ceramic (CEL2) were dispersed in an alkaline solution, with partial dissolution of glass powders. The obtained glass suspensions underwent progressive hardening, by curing at low temperature (40 °C), owing to the formation of a C–S–H (calcium silicate hydrate) gel. As successful direct foaming was achieved by vigorous mechanical stirring of gelified suspensions, comprising also a surfactant. The developed cellular structures were later heat-treated at 900–1000 °C, to form CEL2 glass-ceramic foams, featuring an abundant total porosity (from 60% to 80%) and well-interconnected macro- and micro-sized cells. The developed foams possessed a compressive strength from 2.5 to 5 MPa, which is in the range of human trabecular bone strength. Therefore, CEL2 glass-ceramics can be proposed for bone substitutions. MDPI 2018-02-27 /pmc/articles/PMC5872928/ /pubmed/29495498 http://dx.doi.org/10.3390/ma11030349 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Elsayed, Hamada
Rincón Romero, Acacio
Molino, Giulia
Vitale Brovarone, Chiara
Bernardo, Enrico
Bioactive Glass-Ceramic Foam Scaffolds from ‘Inorganic Gel Casting’ and Sinter-Crystallization
title Bioactive Glass-Ceramic Foam Scaffolds from ‘Inorganic Gel Casting’ and Sinter-Crystallization
title_full Bioactive Glass-Ceramic Foam Scaffolds from ‘Inorganic Gel Casting’ and Sinter-Crystallization
title_fullStr Bioactive Glass-Ceramic Foam Scaffolds from ‘Inorganic Gel Casting’ and Sinter-Crystallization
title_full_unstemmed Bioactive Glass-Ceramic Foam Scaffolds from ‘Inorganic Gel Casting’ and Sinter-Crystallization
title_short Bioactive Glass-Ceramic Foam Scaffolds from ‘Inorganic Gel Casting’ and Sinter-Crystallization
title_sort bioactive glass-ceramic foam scaffolds from ‘inorganic gel casting’ and sinter-crystallization
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872928/
https://www.ncbi.nlm.nih.gov/pubmed/29495498
http://dx.doi.org/10.3390/ma11030349
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