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Peptide nucleic acid-templated selenocystine–selenoester ligation enables rapid miRNA detection
The development of a rapid and chemoselective selenocystine–selenoester peptide ligation that operates at nanomolar reactant concentrations has been developed by utilising PNA templation. Kinetic analysis of the templated peptide ligation revealed that the selenocystine–selenoester reaction was 10 t...
Autores principales: | Sayers, Jessica, Payne, Richard J., Winssinger, Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873163/ https://www.ncbi.nlm.nih.gov/pubmed/29629156 http://dx.doi.org/10.1039/c7sc02736b |
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