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Protein kinase C zeta suppresses low‐ or high‐grade colorectal cancer (CRC) phenotypes by interphase centrosome anchoring

Histological grading provides prognostic stratification of colorectal cancer (CRC) by scoring heterogeneous phenotypes. Features of aggressiveness include aberrant mitotic spindle configurations, chromosomal breakage, and bizarre multicellular morphology, but pathobiology is poorly understood. Prote...

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Detalles Bibliográficos
Autores principales: Deevi, Ravi Kiran, Javadi, Arman, McClements, Jane, Vohhodina, Jekaterina, Savage, Kienan, Loughrey, Maurice Bernard, Evergren, Emma, Campbell, Frederick Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873423/
https://www.ncbi.nlm.nih.gov/pubmed/29520890
http://dx.doi.org/10.1002/path.5035