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Cellular tolerance at the µ-opioid receptor is phosphorylation dependent

Phosphorylation of the μ-opioid receptor (MOR) is known as a key step in desensitization and internalization but the role in the development of long-term tolerance at the cellular level is not known. Viral expression of wild type (exWT) and mutant MORs, where all phosphorylation sites on the C-termi...

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Detalles Bibliográficos
Autores principales:	Arttamangkul, Seksiri, Heinz, Daniel A, Bunzow, James R, Song, Xianqiang, Williams, John T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873894/ https://www.ncbi.nlm.nih.gov/pubmed/29589831 http://dx.doi.org/10.7554/eLife.34989

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