Cargando…

GLP-1 receptor agonist ameliorates obesity-induced chronic kidney injury via restoring renal metabolism homeostasis

Increasing evidence indicates that obesity is highly associated with chronic kidney disease (CKD). GLP-1 receptor (GLP-1R) agonist has shown benefits on kidney diseases, but its direct role on kidney metabolism in obesity is still not clear. This study aims to investigate the protection and metaboli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Chengshi, Li, Ling, Liu, Shuyun, Liao, Guangneng, Li, Lan, Chen, Younan, Cheng, Jingqiu, Lu, Yanrong, Liu, Jingping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5873987/ https://www.ncbi.nlm.nih.gov/pubmed/29590132 http://dx.doi.org/10.1371/journal.pone.0193473

Ejemplares similares

Peritoneal M2 macrophage transplantation as a potential cell therapy for enhancing renal repair in acute kidney injury
por: Mao, Ruiwen, et al.
Publicado: (2020)

Mesenchymal stem cells ameliorate hyperglycemia-induced endothelial injury through modulation of mitophagy
por: Zhu, Wuzheng, et al.
Publicado: (2018)

Control release of mitochondria-targeted antioxidant by injectable self-assembling peptide hydrogel ameliorated persistent mitochondrial dysfunction and inflammation after acute kidney injury
por: Zhao, Meng, et al.
Publicado: (2018)

Early intervention with mesenchymal stem cells prevents nephropathy in diabetic rats by ameliorating the inflammatory microenvironment
por: Li, Yuanmin, et al.
Publicado: (2018)

Mitochondrial ROS promote mitochondrial dysfunction and inflammation in ischemic acute kidney injury by disrupting TFAM-mediated mtDNA maintenance
por: Zhao, Meng, et al.
Publicado: (2021)

Functionalized self-assembling peptide improves INS-1 β-cell function and proliferation via the integrin/FAK/ERK/cyclin pathway
por: Liu, Jingping, et al.
Publicado: (2015)

Mesenchymal Stem Cells Attenuate Diabetic Lung Fibrosis via Adjusting Sirt3-Mediated Stress Responses in Rats
por: Chen, Yang, et al.
Publicado: (2020)

Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis
por: Zeng, Xin, et al.
Publicado: (2020)

Correction to: Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis
por: Zeng, Xin, et al.
Publicado: (2020)

Phloretin attenuates hyperuricemia‐induced endothelial dysfunction through co‐inhibiting inflammation and GLUT9‐mediated uric acid uptake
por: Liu, Shuyun, et al.
Publicado: (2017)

Mesenchymal stem cells alleviate rat diabetic nephropathy by suppressing CD103(+) DCs‐mediated CD8(+) T cell responses
por: Zhang, Fuping, et al.
Publicado: (2020)

Mesenchymal Stem Cells Ameliorated Glucolipotoxicity in HUVECs through TSG-6
por: An, Xingxing, et al.
Publicado: (2016)

Mesenchymal stromal cells protect hepatocytes from lipotoxicity through alleviation of endoplasmic reticulum stress by restoring SERCA activity
por: Li, Linzhao, et al.
Publicado: (2021)

Intervention for early diabetic nephropathy by mesenchymal stem cells in a preclinical nonhuman primate model
por: An, Xingxing, et al.
Publicado: (2019)

Sustained release of hepatocyte growth factor by cationic self-assembling peptide/heparin hybrid hydrogel improves β-cell survival and function through modulating inflammatory response
por: Liu, Shuyun, et al.
Publicado: (2016)

PGC-1α alleviates mitochondrial dysfunction via TFEB-mediated autophagy in cisplatin-induced acute kidney injury
por: Yuan, Longhui, et al.
Publicado: (2021)

MitoEVs: A new player in multiple disease pathology and treatment
por: Zhou, Xiyue, et al.
Publicado: (2023)

Activation of TFEB-mediated autophagy by trehalose attenuates mitochondrial dysfunction in cisplatin-induced acute kidney injury
por: Zhu, Lingling, et al.
Publicado: (2020)

Peritoneal M2 macrophage-derived extracellular vesicles as natural multitarget nanotherapeutics to attenuate cytokine storms after severe infections
por: Wang, Yizhuo, et al.
Publicado: (2022)

Adiponectin gene therapy prevents islet loss after transplantation
por: Wang, Chengshi, et al.
Publicado: (2022)

GLP-1 receptor agonist ameliorates experimental lung fibrosis
por: Fandiño, Juan, et al.
Publicado: (2020)

LRRc17 controls BMSC senescence via mitophagy and inhibits the therapeutic effect of BMSCs on ovariectomy-induced bone loss
por: Liu, Fei, et al.
Publicado: (2021)

Macrophage-derived extracellular vesicles: diverse mediators of pathology and therapeutics in multiple diseases
por: Wang, Yizhuo, et al.
Publicado: (2020)

Extracellular vesicles as advanced therapeutics for the resolution of organ fibrosis: Current progress and future perspectives
por: Lv, Ke, et al.
Publicado: (2022)

Complement C5 activation promotes type 2 diabetic kidney disease via activating STAT3 pathway and disrupting the gut‐kidney axis
por: Li, Ling, et al.
Publicado: (2020)

A preclinical evaluation of alternative site for islet allotransplantation
por: Wang, Chengshi, et al.
Publicado: (2017)

Emerging role of GLP-1 receptor agonists in the treatment of obesity
por: Neff, Lisa M, et al.
Publicado: (2010)

Weak Agonistic LPS Restores Intestinal Immune Homeostasis
por: Steimle, Alex, et al.
Publicado: (2019)

GLP−1 receptor agonists for the treatment of obesity: Role as a promising approach
por: Wang, Jing-Yue, et al.
Publicado: (2023)

Brain GLP‐1 and the regulation of food intake: GLP‐1 action in the brain and its implications for GLP‐1 receptor agonists in obesity treatment
por: Trapp, Stefan, et al.
Publicado: (2021)

Metabolic and gut microbiome changes following GLP-1 or dual GLP-1/GLP-2 receptor agonist treatment in diet-induced obese mice
por: Madsen, Mette Simone Aae, et al.
Publicado: (2019)

β cell aging and age-related diabetes
por: Zhu, Min, et al.
Publicado: (2021)

Indispensable role of mitochondria in maintaining the therapeutic potential of curcumin in acute kidney injury
por: Li, Ling, et al.
Publicado: (2021)

Icariin Ameliorates Diabetic Renal Tubulointerstitial Fibrosis by Restoring Autophagy via Regulation of the miR-192-5p/GLP-1R Pathway
por: Jia, Zhirong, et al.
Publicado: (2021)

GLP-1 receptor agonists (GLP-1RAs): cardiovascular actions and therapeutic potential
por: Ma, Xiaoxuan, et al.
Publicado: (2021)

Future Perspectives on GLP-1 Receptor Agonists and GLP-1/glucagon Receptor Co-agonists in the Treatment of NAFLD
por: Seghieri, Marta, et al.
Publicado: (2018)

Novel GLP-1 Fusion Chimera as Potent Long Acting GLP-1 Receptor Agonist
por: Wang, Qinghua, et al.
Publicado: (2010)

Molecular mechanisms and physiological functions of autophagy in kidney diseases
por: Yang, Jingchao, et al.
Publicado: (2022)

Dual Inhibition of MAPK and JAK2/STAT3 Pathways Is Critical for the Treatment of BRAF Mutant Melanoma
por: Zhao, Kun, et al.
Publicado: (2020)

RNA sequencing data of Vemurafenib-resistant melanoma cells and parental cells
por: Zhao, Kun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_f2unkf1pqrrhssptnt2533brd3