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Interleukin-4 activated macrophages mediate immunity to filarial helminth infection by sustaining CCR3-dependent eosinophilia

Eosinophils are effectors in immunity to tissue helminths but also induce allergic immunopathology. Mechanisms of eosinophilia in non-mucosal tissues during infection remain unresolved. Here we identify a pivotal function of tissue macrophages (Mϕ) in eosinophil anti-helminth immunity using a BALB/c...

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Detalles Bibliográficos
Autores principales:	Turner, Joseph D., Pionnier, Nicolas, Furlong-Silva, Julio, Sjoberg, Hanna, Cross, Stephen, Halliday, Alice, Guimaraes, Ana F., Cook, Darren A. N., Steven, Andrew, Van Rooijen, Nico, Allen, Judith E., Jenkins, Stephen J., Taylor, Mark J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874077/ https://www.ncbi.nlm.nih.gov/pubmed/29547639 http://dx.doi.org/10.1371/journal.ppat.1006949

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