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Dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs

An automatic brain‐metastases planning (ABMP) software has been installed in our institution. It is dedicated for treating multiple brain metastases with radiosurgery on linear accelerators (linacs) using a single‐setup isocenter with noncoplanar dynamic conformal arcs. This study is to validate the...

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Autores principales: Liu, Haisong, Li, Jun, Pappas, Evangelos, Andrews, David, Evans, James, Werner‐Wasik, Maria, Yu, Yan, Dicker, Adam, Shi, Wenyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874088/
https://www.ncbi.nlm.nih.gov/pubmed/27685134
http://dx.doi.org/10.1120/jacmp.v17i5.6320
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author Liu, Haisong
Li, Jun
Pappas, Evangelos
Andrews, David
Evans, James
Werner‐Wasik, Maria
Yu, Yan
Dicker, Adam
Shi, Wenyin
author_facet Liu, Haisong
Li, Jun
Pappas, Evangelos
Andrews, David
Evans, James
Werner‐Wasik, Maria
Yu, Yan
Dicker, Adam
Shi, Wenyin
author_sort Liu, Haisong
collection PubMed
description An automatic brain‐metastases planning (ABMP) software has been installed in our institution. It is dedicated for treating multiple brain metastases with radiosurgery on linear accelerators (linacs) using a single‐setup isocenter with noncoplanar dynamic conformal arcs. This study is to validate the calculated absolute dose and dose distribution of ABMP. Three types of measurements were performed to validate the planning software: 1, dual micro ion chambers were used with an acrylic phantom to measure the absolute dose; 2, a 3D cylindrical phantom with dual diode array was used to evaluate 2D dose distribution and point dose for smaller targets; and 3, a 3D pseudo‐in vivo patient‐specific phantom filled with polymer gels was used to evaluate the accuracy of 3D dose distribution and radiation delivery. Micro chamber measurement of two targets (volumes of 1.2 cc and 0.9 cc, respectively) showed that the percentage differences of the absolute dose at both targets were less than 1%. Averaged GI passing rate of five different plans measured with the diode array phantom was above 98%, using criteria of 3% dose difference, 1 mm distance to agreement (DTA), and 10% low‐dose threshold. 3D gel phantom measurement results demonstrated a 3D displacement of nine targets of [Formula: see text] (range 0.2 ~ 1.1 mm). The averaged two‐dimensional (2D) GI passing rate for several region of interests (ROI) on axial slices that encompass each one of the nine targets was above 98% (5% dose difference, 2 mm DTA, and 10% low‐dose threshold). Measured [Formula: see text] , the minimum dose that covers 95% of the target volume, of the nine targets was 0.7% less than the calculated [Formula: see text]. Three different types of dosimetric verification methods were used and proved the dose calculation of the new automatic brain metastases planning (ABMP) software was clinical acceptable. The 3D pseudo‐in vivo patient‐specific gel phantom test also served as an end‐to‐end test for validating not only the dose calculation, but the treatment delivery accuracy as well. PACS number(s): 87.53.Lv, 87.55.km, 87.55.Qr
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spelling pubmed-58740882018-04-02 Dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs Liu, Haisong Li, Jun Pappas, Evangelos Andrews, David Evans, James Werner‐Wasik, Maria Yu, Yan Dicker, Adam Shi, Wenyin J Appl Clin Med Phys Radiation Oncology Physics An automatic brain‐metastases planning (ABMP) software has been installed in our institution. It is dedicated for treating multiple brain metastases with radiosurgery on linear accelerators (linacs) using a single‐setup isocenter with noncoplanar dynamic conformal arcs. This study is to validate the calculated absolute dose and dose distribution of ABMP. Three types of measurements were performed to validate the planning software: 1, dual micro ion chambers were used with an acrylic phantom to measure the absolute dose; 2, a 3D cylindrical phantom with dual diode array was used to evaluate 2D dose distribution and point dose for smaller targets; and 3, a 3D pseudo‐in vivo patient‐specific phantom filled with polymer gels was used to evaluate the accuracy of 3D dose distribution and radiation delivery. Micro chamber measurement of two targets (volumes of 1.2 cc and 0.9 cc, respectively) showed that the percentage differences of the absolute dose at both targets were less than 1%. Averaged GI passing rate of five different plans measured with the diode array phantom was above 98%, using criteria of 3% dose difference, 1 mm distance to agreement (DTA), and 10% low‐dose threshold. 3D gel phantom measurement results demonstrated a 3D displacement of nine targets of [Formula: see text] (range 0.2 ~ 1.1 mm). The averaged two‐dimensional (2D) GI passing rate for several region of interests (ROI) on axial slices that encompass each one of the nine targets was above 98% (5% dose difference, 2 mm DTA, and 10% low‐dose threshold). Measured [Formula: see text] , the minimum dose that covers 95% of the target volume, of the nine targets was 0.7% less than the calculated [Formula: see text]. Three different types of dosimetric verification methods were used and proved the dose calculation of the new automatic brain metastases planning (ABMP) software was clinical acceptable. The 3D pseudo‐in vivo patient‐specific gel phantom test also served as an end‐to‐end test for validating not only the dose calculation, but the treatment delivery accuracy as well. PACS number(s): 87.53.Lv, 87.55.km, 87.55.Qr John Wiley and Sons Inc. 2016-09-08 /pmc/articles/PMC5874088/ /pubmed/27685134 http://dx.doi.org/10.1120/jacmp.v17i5.6320 Text en © 2016 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Liu, Haisong
Li, Jun
Pappas, Evangelos
Andrews, David
Evans, James
Werner‐Wasik, Maria
Yu, Yan
Dicker, Adam
Shi, Wenyin
Dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs
title Dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs
title_full Dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs
title_fullStr Dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs
title_full_unstemmed Dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs
title_short Dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs
title_sort dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874088/
https://www.ncbi.nlm.nih.gov/pubmed/27685134
http://dx.doi.org/10.1120/jacmp.v17i5.6320
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