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Dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs
An automatic brain‐metastases planning (ABMP) software has been installed in our institution. It is dedicated for treating multiple brain metastases with radiosurgery on linear accelerators (linacs) using a single‐setup isocenter with noncoplanar dynamic conformal arcs. This study is to validate the...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874088/ https://www.ncbi.nlm.nih.gov/pubmed/27685134 http://dx.doi.org/10.1120/jacmp.v17i5.6320 |
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author | Liu, Haisong Li, Jun Pappas, Evangelos Andrews, David Evans, James Werner‐Wasik, Maria Yu, Yan Dicker, Adam Shi, Wenyin |
author_facet | Liu, Haisong Li, Jun Pappas, Evangelos Andrews, David Evans, James Werner‐Wasik, Maria Yu, Yan Dicker, Adam Shi, Wenyin |
author_sort | Liu, Haisong |
collection | PubMed |
description | An automatic brain‐metastases planning (ABMP) software has been installed in our institution. It is dedicated for treating multiple brain metastases with radiosurgery on linear accelerators (linacs) using a single‐setup isocenter with noncoplanar dynamic conformal arcs. This study is to validate the calculated absolute dose and dose distribution of ABMP. Three types of measurements were performed to validate the planning software: 1, dual micro ion chambers were used with an acrylic phantom to measure the absolute dose; 2, a 3D cylindrical phantom with dual diode array was used to evaluate 2D dose distribution and point dose for smaller targets; and 3, a 3D pseudo‐in vivo patient‐specific phantom filled with polymer gels was used to evaluate the accuracy of 3D dose distribution and radiation delivery. Micro chamber measurement of two targets (volumes of 1.2 cc and 0.9 cc, respectively) showed that the percentage differences of the absolute dose at both targets were less than 1%. Averaged GI passing rate of five different plans measured with the diode array phantom was above 98%, using criteria of 3% dose difference, 1 mm distance to agreement (DTA), and 10% low‐dose threshold. 3D gel phantom measurement results demonstrated a 3D displacement of nine targets of [Formula: see text] (range 0.2 ~ 1.1 mm). The averaged two‐dimensional (2D) GI passing rate for several region of interests (ROI) on axial slices that encompass each one of the nine targets was above 98% (5% dose difference, 2 mm DTA, and 10% low‐dose threshold). Measured [Formula: see text] , the minimum dose that covers 95% of the target volume, of the nine targets was 0.7% less than the calculated [Formula: see text]. Three different types of dosimetric verification methods were used and proved the dose calculation of the new automatic brain metastases planning (ABMP) software was clinical acceptable. The 3D pseudo‐in vivo patient‐specific gel phantom test also served as an end‐to‐end test for validating not only the dose calculation, but the treatment delivery accuracy as well. PACS number(s): 87.53.Lv, 87.55.km, 87.55.Qr |
format | Online Article Text |
id | pubmed-5874088 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-58740882018-04-02 Dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs Liu, Haisong Li, Jun Pappas, Evangelos Andrews, David Evans, James Werner‐Wasik, Maria Yu, Yan Dicker, Adam Shi, Wenyin J Appl Clin Med Phys Radiation Oncology Physics An automatic brain‐metastases planning (ABMP) software has been installed in our institution. It is dedicated for treating multiple brain metastases with radiosurgery on linear accelerators (linacs) using a single‐setup isocenter with noncoplanar dynamic conformal arcs. This study is to validate the calculated absolute dose and dose distribution of ABMP. Three types of measurements were performed to validate the planning software: 1, dual micro ion chambers were used with an acrylic phantom to measure the absolute dose; 2, a 3D cylindrical phantom with dual diode array was used to evaluate 2D dose distribution and point dose for smaller targets; and 3, a 3D pseudo‐in vivo patient‐specific phantom filled with polymer gels was used to evaluate the accuracy of 3D dose distribution and radiation delivery. Micro chamber measurement of two targets (volumes of 1.2 cc and 0.9 cc, respectively) showed that the percentage differences of the absolute dose at both targets were less than 1%. Averaged GI passing rate of five different plans measured with the diode array phantom was above 98%, using criteria of 3% dose difference, 1 mm distance to agreement (DTA), and 10% low‐dose threshold. 3D gel phantom measurement results demonstrated a 3D displacement of nine targets of [Formula: see text] (range 0.2 ~ 1.1 mm). The averaged two‐dimensional (2D) GI passing rate for several region of interests (ROI) on axial slices that encompass each one of the nine targets was above 98% (5% dose difference, 2 mm DTA, and 10% low‐dose threshold). Measured [Formula: see text] , the minimum dose that covers 95% of the target volume, of the nine targets was 0.7% less than the calculated [Formula: see text]. Three different types of dosimetric verification methods were used and proved the dose calculation of the new automatic brain metastases planning (ABMP) software was clinical acceptable. The 3D pseudo‐in vivo patient‐specific gel phantom test also served as an end‐to‐end test for validating not only the dose calculation, but the treatment delivery accuracy as well. PACS number(s): 87.53.Lv, 87.55.km, 87.55.Qr John Wiley and Sons Inc. 2016-09-08 /pmc/articles/PMC5874088/ /pubmed/27685134 http://dx.doi.org/10.1120/jacmp.v17i5.6320 Text en © 2016 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Oncology Physics Liu, Haisong Li, Jun Pappas, Evangelos Andrews, David Evans, James Werner‐Wasik, Maria Yu, Yan Dicker, Adam Shi, Wenyin Dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs |
title | Dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs |
title_full | Dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs |
title_fullStr | Dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs |
title_full_unstemmed | Dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs |
title_short | Dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs |
title_sort | dosimetric validation for an automatic brain metastases planning software using single‐isocenter dynamic conformal arcs |
topic | Radiation Oncology Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874088/ https://www.ncbi.nlm.nih.gov/pubmed/27685134 http://dx.doi.org/10.1120/jacmp.v17i5.6320 |
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