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Clinical experience with planning, quality assurance, and delivery of burst‐mode modulated arc therapy

“Burst‐mode” modulated arc therapy (hereafter referred to as “mARC”) is a form of volumetric‐modulated arc therapy characterized by variable gantry rotation speed, static MLCs while the radiation beam is on, and MLC repositioning while the beam is off. We present our clinical experience with the pla...

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Autores principales: Kainz, Kristofer, Prah, Douglas, Ahunbay, Ergun, Li, X. Allen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874115/
https://www.ncbi.nlm.nih.gov/pubmed/27685123
http://dx.doi.org/10.1120/jacmp.v17i5.6253
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author Kainz, Kristofer
Prah, Douglas
Ahunbay, Ergun
Li, X. Allen
author_facet Kainz, Kristofer
Prah, Douglas
Ahunbay, Ergun
Li, X. Allen
author_sort Kainz, Kristofer
collection PubMed
description “Burst‐mode” modulated arc therapy (hereafter referred to as “mARC”) is a form of volumetric‐modulated arc therapy characterized by variable gantry rotation speed, static MLCs while the radiation beam is on, and MLC repositioning while the beam is off. We present our clinical experience with the planning techniques and plan quality assurance measurements of mARC delivery. Clinical mARC plans for five representative cases (prostate, low‐dose‐rate brain, brain with partial‐arc vertex fields, pancreas, and liver SBRT) were generated using a Monte Carlo–based treatment planning system. A conventional‐dose‐rate flat 6 MV and a high‐dose‐rate non‐flat 7 MV beam are available for planning and delivery. mARC plans for intact‐prostate cases can typically be created using one 360° arc, and treatment times per fraction seldom exceed 6 min using the flat beam; using the nonflat beam results in slightly higher MU per fraction, but also in delivery times less than 4 min and with reduced mean dose to distal organs at risk. mARC also has utility in low‐dose‐rate brain irradiation; mARC fields can be designed which deliver a uniform 20 cGy dose to the PTV in approximately 3‐minute intervals, making it a viable alternative to conventional 3D CRT. For brain cases using noncoplanar arcs, delivery time is approximately six min using the nonflat beam. For pancreas cases using the nonflat beam, two overlapping 360° arcs are required, and delivery times are approximately 10 min. For liver SBRT, the time to deliver 800 cGy per fraction is at least 12 min. Plan QA measurements indicate that the mARC delivery is consistent with the plan calculation for all cases. mARC has been incorporated into routine practice within our clinic; currently, on average approximately 15 patients per day are treated using mARC; and with the exception of LDR brain cases, all are treated using the nonflat beam. PACS number(s): 87.55.D‐, 87.55.K‐, 87.53.Ay. 87.56.N‐
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spelling pubmed-58741152018-04-02 Clinical experience with planning, quality assurance, and delivery of burst‐mode modulated arc therapy Kainz, Kristofer Prah, Douglas Ahunbay, Ergun Li, X. Allen J Appl Clin Med Phys Radiation Oncology Physics “Burst‐mode” modulated arc therapy (hereafter referred to as “mARC”) is a form of volumetric‐modulated arc therapy characterized by variable gantry rotation speed, static MLCs while the radiation beam is on, and MLC repositioning while the beam is off. We present our clinical experience with the planning techniques and plan quality assurance measurements of mARC delivery. Clinical mARC plans for five representative cases (prostate, low‐dose‐rate brain, brain with partial‐arc vertex fields, pancreas, and liver SBRT) were generated using a Monte Carlo–based treatment planning system. A conventional‐dose‐rate flat 6 MV and a high‐dose‐rate non‐flat 7 MV beam are available for planning and delivery. mARC plans for intact‐prostate cases can typically be created using one 360° arc, and treatment times per fraction seldom exceed 6 min using the flat beam; using the nonflat beam results in slightly higher MU per fraction, but also in delivery times less than 4 min and with reduced mean dose to distal organs at risk. mARC also has utility in low‐dose‐rate brain irradiation; mARC fields can be designed which deliver a uniform 20 cGy dose to the PTV in approximately 3‐minute intervals, making it a viable alternative to conventional 3D CRT. For brain cases using noncoplanar arcs, delivery time is approximately six min using the nonflat beam. For pancreas cases using the nonflat beam, two overlapping 360° arcs are required, and delivery times are approximately 10 min. For liver SBRT, the time to deliver 800 cGy per fraction is at least 12 min. Plan QA measurements indicate that the mARC delivery is consistent with the plan calculation for all cases. mARC has been incorporated into routine practice within our clinic; currently, on average approximately 15 patients per day are treated using mARC; and with the exception of LDR brain cases, all are treated using the nonflat beam. PACS number(s): 87.55.D‐, 87.55.K‐, 87.53.Ay. 87.56.N‐ John Wiley and Sons Inc. 2016-09-08 /pmc/articles/PMC5874115/ /pubmed/27685123 http://dx.doi.org/10.1120/jacmp.v17i5.6253 Text en © 2016 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Kainz, Kristofer
Prah, Douglas
Ahunbay, Ergun
Li, X. Allen
Clinical experience with planning, quality assurance, and delivery of burst‐mode modulated arc therapy
title Clinical experience with planning, quality assurance, and delivery of burst‐mode modulated arc therapy
title_full Clinical experience with planning, quality assurance, and delivery of burst‐mode modulated arc therapy
title_fullStr Clinical experience with planning, quality assurance, and delivery of burst‐mode modulated arc therapy
title_full_unstemmed Clinical experience with planning, quality assurance, and delivery of burst‐mode modulated arc therapy
title_short Clinical experience with planning, quality assurance, and delivery of burst‐mode modulated arc therapy
title_sort clinical experience with planning, quality assurance, and delivery of burst‐mode modulated arc therapy
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874115/
https://www.ncbi.nlm.nih.gov/pubmed/27685123
http://dx.doi.org/10.1120/jacmp.v17i5.6253
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