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The Phosphodiesterase 4 Inhibitor Roflumilast Protects against Cigarette Smoke Extract-Induced Mitophagy-Dependent Cell Death in Epithelial Cells

BACKGROUND: Recent studies show that mitophagy, the autophagy-dependent turnover of mitochondria, mediates pulmonary epithelial cell death in response to cigarette smoke extract (CSE) exposure and contributes to the development of emphysema in vivo during chronic cigarette smoke (CS) exposure, altho...

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Detalles Bibliográficos
Autores principales:	Kyung, Sun Young, Kim, Yu Jin, Son, Eun Suk, Jeong, Sung Hwan, Park, Jeong-Woong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Academy of Tuberculosis and Respiratory Diseases 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874143/ https://www.ncbi.nlm.nih.gov/pubmed/29589382 http://dx.doi.org/10.4046/trd.2017.0115

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