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Targeting MDMX and PKCδ to improve current uveal melanoma therapeutic strategies

Uveal melanoma (UM) is the most frequent ocular cancer in adults, accounting for ~5% of the total melanoma incidence. Although the primary tumor is well treatable, patients frequently develop metastases for which no curative therapy exists. Highly activated protein kinase C (PKC) is a common feature...

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Detalles Bibliográficos
Autores principales: Heijkants, R. C., Nieveen, M., Hart, K. C.’t, Teunisse, A. F. A. S., Jochemsen, A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874255/
https://www.ncbi.nlm.nih.gov/pubmed/29593251
http://dx.doi.org/10.1038/s41389-018-0041-y

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