Leptin-induced inflammation by activating IL-6 expression contributes to the fibrosis and hypertrophy of ligamentum flavum in lumbar spinal canal stenosis

The ongoing chronic inflammation and subsequent fibrosis play an important role in ligamentum flavum (LF) fibrosis and hypertrophy in patients with lumbar spinal canal stenosis (LSCS). Leptin is a chronic inflammatory mediator and involved in the fibrotic process in multiple organ systems. The prese...

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Detalles Bibliográficos
Autores principales: Sun, Chao, Wang, Zhen, Tian, Ji-Wei, Wang, Yun-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874260/
https://www.ncbi.nlm.nih.gov/pubmed/29436483
http://dx.doi.org/10.1042/BSR20171214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874260/
https://www.ncbi.nlm.nih.gov/pubmed/29436483
http://dx.doi.org/10.1042/BSR20171214

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