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In Situ Proximity Ligation Assay Reveals Co-Localization of Alpha-Synuclein and SNARE Proteins in Murine Primary Neurons

The aggregation of alpha-synuclein (αSyn) is the pathological hallmark of Parkinson’s disease, dementia with Lewy bodies and related neurological disorders. However, the physiological function of the protein and how this function relates to its pathological effects remain poorly understood. One of t...

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Detalles Bibliográficos
Autores principales: Almandoz-Gil, Leire, Persson, Emma, Lindström, Veronica, Ingelsson, Martin, Erlandsson, Anna, Bergström, Joakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874290/
https://www.ncbi.nlm.nih.gov/pubmed/29623065
http://dx.doi.org/10.3389/fneur.2018.00180