Cargando…
In Situ Proximity Ligation Assay Reveals Co-Localization of Alpha-Synuclein and SNARE Proteins in Murine Primary Neurons
The aggregation of alpha-synuclein (αSyn) is the pathological hallmark of Parkinson’s disease, dementia with Lewy bodies and related neurological disorders. However, the physiological function of the protein and how this function relates to its pathological effects remain poorly understood. One of t...
Autores principales: | Almandoz-Gil, Leire, Persson, Emma, Lindström, Veronica, Ingelsson, Martin, Erlandsson, Anna, Bergström, Joakim |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874290/ https://www.ncbi.nlm.nih.gov/pubmed/29623065 http://dx.doi.org/10.3389/fneur.2018.00180 |
Ejemplares similares
-
Mapping of Surface-Exposed Epitopes of In Vitro and In Vivo Aggregated Species of Alpha-Synuclein
por: Almandoz-Gil, Leire, et al.
Publicado: (2016) -
Altered Distribution of SNARE Proteins in Primary Neurons Exposed to Different Alpha-Synuclein Proteoforms
por: Brolin, Emma, et al.
Publicado: (2023) -
Alpha-synuclein oligomer-selective antibodies reduce intracellular accumulation and mitochondrial impairment in alpha-synuclein exposed astrocytes
por: Gustafsson, Gabriel, et al.
Publicado: (2017) -
Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes
por: Rostami, Jinar, et al.
Publicado: (2017) -
Early fine motor impairment and behavioral dysfunction in (Thy‐1)‐h[A30P] alpha‐synuclein mice
por: Ekmark‐Lewén, Sara, et al.
Publicado: (2018)