Nonmyelomatous Ascites Resulting from the Increased Secretion of Vascular Endothelial Growth Factor in Multiple Myeloma

Ascites is a rare complication of multiple myeloma (MM); in most cases, the direct invasion of myeloma cells to the peritoneal cavity has been assumed to be the etiology because the effusion is usually exudative and contains a high proportion of myeloma cells. We herein report a case of MM with mass...

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Autores principales: Maki, Hiroaki, Nannya, Yasuhito, Imai, Yoichi, Yamaguchi, Satoko, Kamikubo, Yasuhiko, Ichikawa, Motoshi, Nakamura, Fumihiko, Kurokawa, Mineo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874348/
https://www.ncbi.nlm.nih.gov/pubmed/29151500
http://dx.doi.org/10.2169/internalmedicine.8886-17
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author Maki, Hiroaki
Nannya, Yasuhito
Imai, Yoichi
Yamaguchi, Satoko
Kamikubo, Yasuhiko
Ichikawa, Motoshi
Nakamura, Fumihiko
Kurokawa, Mineo
author_facet Maki, Hiroaki
Nannya, Yasuhito
Imai, Yoichi
Yamaguchi, Satoko
Kamikubo, Yasuhiko
Ichikawa, Motoshi
Nakamura, Fumihiko
Kurokawa, Mineo
author_sort Maki, Hiroaki
collection PubMed
description Ascites is a rare complication of multiple myeloma (MM); in most cases, the direct invasion of myeloma cells to the peritoneal cavity has been assumed to be the etiology because the effusion is usually exudative and contains a high proportion of myeloma cells. We herein report a case of MM with massive ascites containing only a small amount of myeloma cells. Instead, high levels of serum and ascitic vascular endothelial growth factor were detected. This was suggested to be a potential mechanism underlying the development of ascites.
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spelling pubmed-58743482018-03-29 Nonmyelomatous Ascites Resulting from the Increased Secretion of Vascular Endothelial Growth Factor in Multiple Myeloma Maki, Hiroaki Nannya, Yasuhito Imai, Yoichi Yamaguchi, Satoko Kamikubo, Yasuhiko Ichikawa, Motoshi Nakamura, Fumihiko Kurokawa, Mineo Intern Med Case Report Ascites is a rare complication of multiple myeloma (MM); in most cases, the direct invasion of myeloma cells to the peritoneal cavity has been assumed to be the etiology because the effusion is usually exudative and contains a high proportion of myeloma cells. We herein report a case of MM with massive ascites containing only a small amount of myeloma cells. Instead, high levels of serum and ascitic vascular endothelial growth factor were detected. This was suggested to be a potential mechanism underlying the development of ascites. The Japanese Society of Internal Medicine 2017-11-20 2018-03-01 /pmc/articles/PMC5874348/ /pubmed/29151500 http://dx.doi.org/10.2169/internalmedicine.8886-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Maki, Hiroaki
Nannya, Yasuhito
Imai, Yoichi
Yamaguchi, Satoko
Kamikubo, Yasuhiko
Ichikawa, Motoshi
Nakamura, Fumihiko
Kurokawa, Mineo
Nonmyelomatous Ascites Resulting from the Increased Secretion of Vascular Endothelial Growth Factor in Multiple Myeloma
title Nonmyelomatous Ascites Resulting from the Increased Secretion of Vascular Endothelial Growth Factor in Multiple Myeloma
title_full Nonmyelomatous Ascites Resulting from the Increased Secretion of Vascular Endothelial Growth Factor in Multiple Myeloma
title_fullStr Nonmyelomatous Ascites Resulting from the Increased Secretion of Vascular Endothelial Growth Factor in Multiple Myeloma
title_full_unstemmed Nonmyelomatous Ascites Resulting from the Increased Secretion of Vascular Endothelial Growth Factor in Multiple Myeloma
title_short Nonmyelomatous Ascites Resulting from the Increased Secretion of Vascular Endothelial Growth Factor in Multiple Myeloma
title_sort nonmyelomatous ascites resulting from the increased secretion of vascular endothelial growth factor in multiple myeloma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874348/
https://www.ncbi.nlm.nih.gov/pubmed/29151500
http://dx.doi.org/10.2169/internalmedicine.8886-17
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