iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation

We launched an integrative multi-omics database, iMETHYL (http://imethyl.iwate-megabank.org). iMETHYL provides whole-DNA methylation (~24 million autosomal CpG sites), whole-genome (~9 million single-nucleotide variants), and whole-transcriptome (>14 000 genes) data for CD4(+) T-lymphocytes, mono...

Descripción completa

Detalles Bibliográficos
Autores principales: Komaki, Shohei, Shiwa, Yuh, Furukawa, Ryohei, Hachiya, Tsuyoshi, Ohmomo, Hideki, Otomo, Ryo, Satoh, Mamoru, Hitomi, Jiro, Sobue, Kenji, Sasaki, Makoto, Shimizu, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Data Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874393/
https://www.ncbi.nlm.nih.gov/pubmed/29619235
http://dx.doi.org/10.1038/hgv.2018.8
Descripción
Sumario:We launched an integrative multi-omics database, iMETHYL (http://imethyl.iwate-megabank.org). iMETHYL provides whole-DNA methylation (~24 million autosomal CpG sites), whole-genome (~9 million single-nucleotide variants), and whole-transcriptome (>14 000 genes) data for CD4(+) T-lymphocytes, monocytes, and neutrophils collected from approximately 100 subjects. These data were obtained from whole-genome bisulfite sequencing, whole-genome sequencing, and whole-transcriptome sequencing, making iMETHYL a comprehensive database.

Ejemplares similares